L-97-034-PB

Adsorption / desorption

Administrative data

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

13th - 26th September 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

Deviations:

no

GLP compliance:

yes

Type of method:

HPLC estimation method

Media:

soil

Test material

Test material information

Constituent 1

Reference substance name:

Pentaerythritol mixed esters with 2-methyl butyric acid, n-pentanoic acid, n-heptanoic acid, 3,5,5-trimethylhexanoic acid, n-octanoic acid, n-decanoic acid

Cas Number:

141686-49-9

IUPAC Name:

Pentaerythritol mixed esters with 2-methyl butyric acid, n-pentanoic acid, n-heptanoic acid, 3,5,5-trimethylhexanoic acid, n-octanoic acid, n-decanoic acid

Constituent 2

Reference substance name:

Trimethylol propane mixed esters with 2-methyl butyric acid, n-pentanoic acid, n-heptanoic acid, 3,5,5-trimethylhexanoic acid, n-octanoic acid, n-decanoic acid

Cas Number:

141686-50-2

IUPAC Name:

Trimethylol propane mixed esters with 2-methyl butyric acid, n-pentanoic acid, n-heptanoic acid, 3,5,5-trimethylhexanoic acid, n-octanoic acid, n-decanoic acid

Test material form:

liquid

Details on test material:

Identification: Hatcol ® 1772
Appearance/physical state: Clear colorless liquid
Purity: 100% (no solvent present)
Composition: 70% pentaerythritol esters described by CAS# 141686-49-9; 30% trimethylolpropane esters described by CAS# 141686-50-2

Radiolabelling:

no

Study design

HPLC method

Details on study design: HPLC method:

HPLC System: Agilent Technologies 1100, incorporating workstation and autosampler
Detector type: variable wavelength (VW)
Column: Waters XSelect HSS CYANO 5μm (150 x 4.6 mm id)
Column temperature: 30 °C
Mobile phase: Methanol:purified water (55:45 v/v)
pH of mobile phase: 6.6
Flow-rate: 1.0 mL/min
Injection volume: 10 μL
VW detector wavelength: 210 nm

The mobile phase was ramped to 100% methanol shortly after the elution of the last reference standard in order to elute any highly retained test item components. This was carried out for the sample and sample blank injections only.

Results and discussion

Adsorption coefficient

Adsorption coefficient 1

Key result

Sample No.:

#1

Type:

log Koc

Value:

> 5.63 dimensionless

Adsorption coefficient 2

Key result

Sample No.:

#2

Type:

log Koc

Value:

> 5.63 dimensionless

Applicant's summary and conclusion

Validity criteria fulfilled:

not applicable

Conclusions:

The adsorption coefficient (Koc) of Hatcol® 1772 has been determined to be greater than 4.3 x 105, log10 Koc >5.63, using the HPLC screening method.

Executive summary:

The adsorption coefficient (K_oc) of Hatcol® 1772 has been determined to be greater than 4.3 x 10⁵, log₁₀K_oc >5.63, using the HPLC screening method, designed to be compatible with Method C.19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001. The results classify the test item as being immobile.