Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 204-973-4 | CAS number: 130-00-7
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only very limited informations about the test conditions available.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 977
Materials and methods
Test guideline
- Guideline:
- other: BASF Methode
- GLP compliance:
- no
Test material
- Reference substance name:
- Naphthollactam
- IUPAC Name:
- Naphthollactam
- Reference substance name:
- 2-Oxobenzindol
- IUPAC Name:
- 2-Oxobenzindol
Constituent 1
Constituent 2
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- no
- Amount / concentration applied:
- 50 mg
- Observation period (in vivo):
- 8 d
- Number of animals or in vitro replicates:
- no data
Results and discussion
In vivo
Results
- Remarks on result:
- probability of mild irritation
- Remarks:
- Only a study summary is available, with no details.
Any other information on results incl. tables
24 h after treatment a slight redness and slight edema was observed, which were fully reversible within 8 days.
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: expert judgment
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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