3-dimethylaminopropan-1-ol

Short-term toxicity to aquatic invertebrates

Description of key information

With high probability acutely not harmful to aquatic invertebrates

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

112 mg/L

Additional information

The acute toxicity of 3 -dimethylpropanol (CAS 3179 -63 -3) to aquatic invertebrates was tested according to German Industrial Standard DIN 38412, Part 11 in two studies. The EC50 was determined to be greater than 100 mg/L (112 and 166 mg/L; BASF AG, 1989; report no. 89/1347 - Massenzucht and report no. 8971347 - Einzelzucht). The effect of the substance on the mobility of D. magna is probably in part due to pH changes caused by the substance. In both studies a neutralised sample of the highest concentration (320 and 580 mg/L) was tested in parallel. The toxicity of the test item was reduced. At 500 mg/L, the effects were delayed in time as all daphnids were immobilised in the neutralised 580 mg/L sample after 48 h while in the not-neutralised sample the daphnids were immobilised already after 3 h. At 320 mg/L, the toxicity was reduced to 45% after 48 h compared to 100% in the not-neutralised sample.

The test item concentrations were not analytically verified, but are assumed to be stable, due to the the low n-octanol/water partition coefficient (log Kow = -0.23 at 25°C, pH 10.7; log Kow = -2.59 at 25°C, pH 7.2 ), the high water solubility (WS = 1.0E+06 mg/L at 20 °C), the moderate vapour pressure (VP = 1.56 hPa at 20 °C) and the low Henry´s law constant (HLC, uncharged: 0.016 Pa*m³/mol) of the substance.