Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Accepted calculation method.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Principles of method if other than guideline:
Predited oral rat LD50 from Cosenses method
GLP compliance:
no
Test type:
other: QSAR calculation

Test material

Constituent 1
Chemical structure
Reference substance name:
[4-(4-fluorobenzoyl)phenyl](4-fluorophenyl)methanone
EC Number:
619-535-1
Cas Number:
68418-51-9
Molecular formula:
C20H12F2O2
IUPAC Name:
[4-(4-fluorobenzoyl)phenyl](4-fluorophenyl)methanone

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Details on study design:
Data available from US EPA Toxicity Estimation Software Tool (T.E.S.T.) Consensus method

Results and discussion

Effect levels
Effect level:
ca. 939.88 mg/kg bw
Based on:
not specified
Remarks on result:
other: QSAR

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Material is tobe classified as Acute Toxicity Category 4 (oral).