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Diss Factsheets
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EC number: 940-936-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.449 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.045 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 2.515 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Target substance is usually maintained in pH above 11 because it becomes unstable if pH drops below 9. In very low pH (<4) the substance will release chlorine gas. When substance is introduced to test conditions, it will become unstable making analytical quantification difficult.
Because of these properties of test substance, samples of test medium in the key studies were not collected during the exposure period for the analytical verification of the test solutions. Test substance could not be quantified in the test system due to the nature of the material being unstable under the test conditions and the fact that no suitable analytical technique with the required sensitivity could be determined. The results of key studies were based on nominal test concentrations
The key studies used in the PNEC derivation and C&L were conducted on the test substance complying with GLP and fulfilling OECD guidelines. Short-term toxicity to fish for fresh and salt water were based on read-across data from studies conducted on analogue substance sodium hypochlorite. These studies were not done according GLP or guidelines and did not have enough information on the test conditions or methodology and therefore they were not used for C&L purposes. However, they were used as Weight of Evidence approach to evaluate the acute toxicity effects and the hazard assessment.
Conclusion on classification
The following key information is used for the classification of the target substance:
Acute aquatic toxicity:
Toxicity to algae (Pseudokirchneriella subcapitata): 72 -h EC50 449 µg/l and NOEC 215 µg/l (OECD 201, GLP)
Toxicity to invertebrates (Daphnia magna): 48 -h EC50 0.94 mg/l (OECD 202, GLP)
Short-term toxicity to freshwater fish (Leiostomus xanthurus): 96-h LC50 0.09 mg/l (read-across, WoE, non-guideline study)
Short-term toxicity to marine water fish (Oncorhynchus kisutch): 96 -h LC50 0.03 mg/l (read-across, WoE, non-guideline study)
Respiratory inhibition of activated sludge: 3-h EC50 251.5 mg/l (OECD 209; GLP)
Conclusion:
The target substance is classified to hazard class: Aquatic Acute Toxic cat. 1 because the lowest toxicity value indicate the EC/LC50 value is (448 g/µl, 72 -h ErC50, Pseudokirchneriella subcapitata) below 1 mg/l. The M-factor is 1 based on lowest EC50 value being between 0.1 mg/L < and ≤ 1 mg/L.
Chronic aquatic toxicity:
Since no long-term aquatic toxicity results are available the toxicity is evaluated based on the short-term study results and the degradation and bioaccumulation properties.
Acute toxicity:
EC/LC50-value <1 mg/l (448 g/µl, 72 -h ErC50, Pseudokirchneriella subcapitata).
Degradation and bioaccumulation:
Bio-degradation is not an important fate process for the substance. The organic chemical groups in the reaction products will be biodegradable but the ultimate decomposition reactions are, based on the known reactions of free available chlorine, resulting inorganic reaction products not relevant for biodegradation. This substance degrades abiotically, and the half-life is dependent on the environmental conditions such as pH, temperature and organic matter. The ultimate degradation product is chloride. The estimated log Kow values for the reaction mass components are within a range of -4.18 to -1.89, and the estimated BCF factor around 3.16 L/kg (US EPA 2014). Therefore, the substance is not considered as persistent and/or bioaccumulative.
Conclusion:
Not to be classified for any of the aquatic chronic hazard classes. The analogue household bleaches (e.g. sodium hypochlorite) have also harmonised classification entry in CLP Annex VI for Aquatic Acute 1 H400. The available chlorine concentration of the target substance is appr. 7.7-8.6 % though no need to consider this substance as having chronic aquatic toxicity.
Classification and labelling:
CLP 1272/2008:
Aquatic Acute 1, H400
M-factor 1
DSD 67/548/EEC:
N; R50
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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