Registration Dossier
Registration Dossier
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EC number: 700-445-7 | CAS number: 846023-54-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 8-14 September 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Organisation for Economic Co-operation and Development (OECD), OECD Guidelines for Testing of Chemicals, Draft Proposal for a New Guideline: In Vitro Skin Irritation: Reconstructed Human Epidermis (RhE) Test Method.
- Qualifier:
- according to guideline
- Guideline:
- other: European Community (EC). Commission regulation (EC) No. 761/2009, Part B: Methods for the Determination of Toxicity and other health effects, Guideline B.46 “In Vitro Skin Irritation: Reconstructed Human Epidermis Model Test ". Official Journal of the Eur
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1-[3-(2-methoxy-5-nitrophenoxy)propyl]-4-methylpiperazine
- EC Number:
- 700-445-7
- Cas Number:
- 846023-54-9
- Molecular formula:
- C15H23N3O4
- IUPAC Name:
- 1-[3-(2-methoxy-5-nitrophenoxy)propyl]-4-methylpiperazine
Constituent 1
Test animals
- Species:
- other: not applicable
- Strain:
- other: not applicable
Test system
- Type of coverage:
- other: not applicable
- Preparation of test site:
- other: not applicable
- Vehicle:
- other: not applicable
- Controls:
- other: not applicable
- Observation period:
- not applicable
- Number of animals:
- not applicable
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
- Conclusions:
- Finally, it is concluded that this test is valid and that WAY-190192-A is non-irritant in the in vitro
skin irritation test under the experimental conditions described in this report.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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