Registration Dossier
Registration Dossier
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EC number: 208-173-6 | CAS number: 513-85-9
Endpoint summary
Administrative data
Description of key information
The test item is neither irritating to skin nor irritating to the eyes.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
skin irritation
The potential of the test item to cause acute dermal irritation or corrosion was assessed by a single topical application of 0.5 mL of the test substance to the intact skin of 6 white Vienna White rabbits (3 male and 3 female) (BASF AG 1980). The average score (24 to 72 hours) for irritation was calculated to be 1.0 for erythema and 0.9 for edema. The effects were fully reversible within 8 d. Under the test conditions chosen and considering the described findings the test item does not give indication of an irritant property to the skin.
eye irritation
The potential of the test item to cause damage to the eye was assessed in 6 white Vienna White rabbits (3 male and 3 female), subjected to a single ocular application of 0.1 mL of the test substance (BASF SE 1980). The average score (24 to 72 hours) for irritation was calculated to be 0.0 for corneal opacity, 0.0 for iris, and 0.7 for conjunctivae redness. Under the test conditions chosen and considering the described findings, the test item does not give indication of an irritant property to the skin.
Justification for classification or non-classification
No classification and labelling for skin or eye irritation is necessary according to Directive 67/548/EEC(DSD) or Regulation (EC) No 1272/2008 (GHS (EU-CLP)) criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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