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Diss Factsheets
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EC number: 254-959-7 | CAS number: 40530-60-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 1980
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- Pre-guideline test according to internal SOP (Method A-11).
- Deviations:
- not applicable
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- yes
- Details on test solutions:
- FAT 36052/E was dissolved with acetone and in parallel and in another experiment FAT 36052/E was dissolved in Tween 80.
- Test organisms (species):
- other: forellen (trout) as well as Red killi
- Details on test organisms:
- Experiment with trouts and acetone as vehicle: 8 trouts each conc were used;
Experiment with trouts and Tween 80 as vehicle: 8 trouts each conc were used;
Experiment with Red Killi and Tween 80 as vehicle: 10 fish each conc were used. - Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- Experiments with trouts: 14 °C
Experiment with Red killi: 25 °C - pH:
- 7.9 - 8.1
- Nominal and measured concentrations:
- Experiment with trouts and acetone as vehicle: 100, 200 and 1000 mg/l
Experiment with trouts and Tween 80 as vehicle: 100, 200 and 1000 mg/l
Experiment with Red Killi and Tween 80 as vehicle: 200 and 1000 mg/l - Details on test conditions:
- 8 trouts were used for the experiment.
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC0
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- Experiment with trout and acetone as vehicle (conc used - 100, 200 and 1000 mg/l): no mortality;
Experiment with trout and Tween 80 as vehicle (conc used - 100, 200 and 1000 mg/l): no mortality;
Experiment with Red Killi and Tween 80 as vehicle (conc used - 200 and 1000 mg/l): no mortality at 200 mg/l, however 1 out of 10 fish was found dead at 48 hours with the concentration 100 mg/l. - Validity criteria fulfilled:
- not specified
- Conclusions:
- LC50 for FAT 36052/E was found to be >1000 mg/l.
- Executive summary:
The acute fish toxicity was investigated in three different experiments. In an experiment with trouts and acetone as vehicle including concentrations of 100, 200 and 1000 mg/l tested on eight touts each. No motality was observed. In a second experiment with trouts and Tween 80 as vehicle concentrations of 100, 200 and 1000 mg/l tested on 8 trouts each also resulted in no mortality. A third experiment with Red Killi and Tween 80 as vehicle involving 200 and 1000 mg/l tested on 10 fish each 1 death occured at 1000 mg/l concentration level, only. Based on these experiments, LC50for FAT 36052/E was found to be >1000 mg/l.
Reference
Description of key information
The acute fish toxicity was investigated in three different experiments. In an experiment with trouts and acetone as vehicle including concentrations of 100, 200 and 1000 mg/l tested on eight touts each. No motality was observed. In a second experiment with trouts and Tween 80 as vehicle concentrations of 100, 200 and 1000 mg/l tested on 8 trouts each also resulted in no mortality. A third experiment with Red Killi and Tween 80 as vehicle involving 200 and 1000 mg/l tested on 10 fish each 1 death occured at 1000 mg/l concentration level, only. Based on these experiments, LC50 for FAT 36052/E was found to be >1000 mg/l.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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