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EC number: 262-062-7 | CAS number: 60113-43-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
LD50, rat, oral (gavage) = 2000 mg/kg (BASF AG, 1985)
Inhalation Hazard Test: No mortality was observed after inhalation of a highly saturated vapor-air-mixture for 7 hours in rats (BASF AG, 1986)
Key value for chemical safety assessment
Additional information
Oral:
The key study was performed according to a BASF-internal method equivalent or similar to OECD guideline 401 (BASF AG, 1985). The test substance was administered as a solution in olive oil via gavage to five fasted Wistar rats per sex and dose at dose levels of 1000, 1470, 2150, and 3160 mg/kg bw followed by a 14-day observation period. The LD50 was determined to be 2000 mg/kg bw in males and females (ca. 1470 mg/kg bw in females, ca. 2850 mg/kg bw in males). Clinical symptoms comprised dyspnea, apathy, abnormal position, staggering atonia, paresis, pain relfex absent, corenal reflex absent, narcotic-like state, twitching, piloerection, diarrhea, erythema, exsiccosis, imbalance, and poor general state in bothe sexes. In addition, tremor and lacrimation was observed in female animals. At necropsy, general congestive hyperemia and dilated stomach filled with feed and liquid contents were observed in animals that died. no abnormalities were detected in the sacrificed animals.
Inhalation:
No mortality occured in an acute vapour inhalation study comparable to the inhalation hazard test described in the Annex of OECD Guideline 403 with acceptable restrictions (non-GLP, low number of animals). In this study 3 male and 3 female Wistar rats were exposed for 7 hours to the saturated vapour of the test substance. Clinical signs during exposure were an accelerated, in some animals intermittent, respiration, slight attempts to escape, wiping of snouts, and trembling in some animals. After exposure no clinical signs were observed. No mortality occurred during the 14-day post-exposure observation period. Nothing abnormal was detected in the organs at necropsy.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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