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EC number: 231-869-6 | CAS number: 7773-01-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
- Endpoint:
- fish early-life stage toxicity
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted on read-across material
- Justification for type of information:
- See the read-across report attached in Section 13
Cross-reference
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint:
- fish early-life stage toxicity
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted on read-across material
- Remarks:
- Study conducted to basic scientific principles. Read-across from MnSO4 to MnCl2 is considered scientifically valid, as the anions are not expected to exhibit different ecotoxicity and in both cases the cation Mn2+ is common to both substances and both substances are very soluble in water.
- Justification for type of information:
- See the read-across report attached in Section 13.
- Reason / purpose for cross-reference:
- other: Read-across target
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Two sets of eyed rainbow trout eggs were used for testing, one set were acclimatised to manganese from the egg stage and one unacclimatised set.
Fish eggs were exposed to concentrations of the test material delivered via proportional diluted at a rate of two litres of test solution per cycle.
Under similar conditions, unexposed fish eggs were exposed to the same water conditions except no MnSO4 added. - GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 4 mo
- Duration:
- 4 mo
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.6 mg/L
- Conc. based on:
- other: Mn
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The study showed an increased tolerance of rainbow trout eggs chronically exposed to Mn2+ compared to unexposed eggs. The No Observed Effect Concentration (NOEC) was 0.60 mg Mn/L in soft water.
Effect/no effect concentration and chronic value data show about a 2X increase in tolerance of exposed rainbow trout eggs
Table 1: Toxicity values
Effect/no effect conc. mg/L |
Chronic value mg/L |
|
Acclimatised |
2.13 - 1.15 |
1.57 |
Unacclimatised |
1.04 - 0.60 |
0.79 |
Table 2: Measured Mn concentration and mortality data
Exposure |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
|
Acclimatised group |
||||||
Mn (mg/L) |
6.61 |
5.08 |
3.74 |
2.13 |
1.15 |
0.61 |
<0.02 |
Std Dev |
0.51 |
0.33 |
0.25 |
0.17 |
0.09 |
0.04 |
0.03 |
N |
4 |
18 |
18 |
18 |
18 |
18 |
18 |
% mortality |
100 |
95 |
90 |
35 |
0 |
0 |
0 |
|
Unacclimatised group |
||||||
Mn (mg/L) |
6.50 |
4.58 |
3.49 |
1.96 |
1.40 |
0.60 |
<0.02 |
Std Dev |
0.35 |
0.36 |
0.18 |
0.12 |
0.12 |
0.14 |
0.03 |
N |
5 |
5 |
18 |
18 |
18 |
18 |
18 |
% mortality |
100 |
100 |
95 |
60 |
10.5 |
0 |
0 |
Table 3: Water quality data
|
Alkalinity mg/L |
Hardness mg/L |
pH |
D.O. mg/L |
Temp °C |
Mean |
39.4 |
34.0 |
7.53 |
7.73 |
14.3 |
Water quality values were incorrectly reported in the paper. Corrected values are reported as an addendum in: Davies & Brinkman, (1995) Acute toxicity of manganese to Brown Trout (Salmo trutta) in hard water, Federal aid project #F-243, Colorado Division of Wildlife, Fort Collins, Colorado
Data source
Reference
- Reference Type:
- publication
- Title:
- Acute and chronic toxicity of manganese to exposed and unexposed Rainbow and brown trout
- Author:
- Davies P & Brinkman S
- Year:
- 1 994
- Bibliographic source:
- Federal aid project F-243-1, Colorado Division of Wildlife, Fort Collins, Colorado
Materials and methods
Test material
- Reference substance name:
- Manganese dichloride
- EC Number:
- 231-869-6
- EC Name:
- Manganese dichloride
- Cas Number:
- 7773-01-5
- Molecular formula:
- Cl2Mn
- IUPAC Name:
- manganese(2+) dichloride
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 4 mo
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.6 mg/L
- Conc. based on:
- other: Mn
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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