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Diss Factsheets
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EC number: 203-897-9 | CAS number: 111-70-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Apart from industrial production, it has to be underlined that heptan-1-ol is a natural product found in plants, meats, fruits, vegetables and even in the air exhaled by healthy, unexposed people.
When released to water
If released into water, heptan-1-ol is not expected to adsorb to suspended solids and sediments due to its low potential of adsorption (log Kow = 2.2; Gancet, 2009). Volatilization from water surfaces is expected to be a significant fate process based upon the Henry’s Law constant for this compound. Estimated volatilization half-lives for a model river and model lake are 2.2 days and 20 days, respectively. In contrast, hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. The hydrolysis as a function of pH of the test item n-heptanol was assessed according to the OECD guideline 111. The preliminary test showed that the item was stable at pH 4, 7 and 9 at 50 +1- 0.5 °C. No decomposition products could be detected by the analysis and less than 10% was hydrolyzed after five days for each of the three buffers. Consequently, heptan-1-ol can be considered as stable under the tested conditions (pH = 4, 7 and 9).
The ready biodegradability of heptan-1-ol was evaluated in a study (Gancet, 2011) performed in accordance with OECD testing guideline 301 F and GLP requirements. According to these results, heptanol is considered as readily biodegradable.
When released to soil/sediments
Heptan-1-ol is characterized by a low potential of adsorption based on its log Kow value of 2.2 (Gancet, 2009). Consequently, it is expected to have a high degree of mobility in soil and sediment compartments. In accordance with column 2 of REACH Annex IX, the adsorption/desorption screening test does not need to be conducted as the substance can be expected to have a low potential for adsorption based on its intrinsic properties (log Kow = 2.2). Nevertheless, an experimental study is available. This study confirms that heptan-1-ol will not adsorb on soil and sediment particulate matters. The log Koc value was estimated at 1.66.
Besides, it has been demonstrated that heptan-1-ol is readily biodegradable. Consequently, soil and sediment compartments are not considered target compartments for heptan-1-ol. Thus, no further tests are proposed.
Heptan1-1-ol is expected to be mobile in soil and sediments and its identified target compartment will be the atmospheric compartment, due to volatilization from water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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