Registration Dossier
Registration Dossier
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EC number: 426-400-9 | CAS number: 170222-39-6
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 31, 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Version / remarks:
- 1984
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Red RA 10463
- IUPAC Name:
- Red RA 10463
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- Because the test substance was hardly soluble in water, a suspension of 0.5 g/l was prepared using Tween-80 as additive.
Test organisms
- Test organisms (species):
- activated sludge
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 30 min
Test conditions
- Test temperature:
- 20.3 °C
- pH:
- 7.4 - 7.7
- Nominal and measured concentrations:
- - Nominal concentration: 100 mg/L in duplicate
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-dichlorophenol: 3.2, 10, 32 mg/l
Results and discussion
Effect concentrations
- Duration:
- 30 min
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Details on results:
- No significant inhibition in respiration rate was recorded between the treatment, control and additive control groups (significant: > 10 %).
- Results with reference substance (positive control):
- EC50 (30 minutes) = 9 mg/l
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Not toxic to waste-water bacteria at 100 mg/l upon an exposure time of 30 minutes.
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