Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 425-380-9 | CAS number: 7397-46-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Remarks:
- other: ex-vivo
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Information from migrated NONS file.
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
- Principles of method if other than guideline:
- Due to the pyrophoric nature of the test substance (instable in air) an 'ex-vivo' study using non-living animals and
non-living animal skin was performed. - GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 425-380-9
- EC Name:
- -
- Cas Number:
- 7397-46-8
- Molecular formula:
- C5H13BO
- IUPAC Name:
- methyl diethylborinate
Constituent 1
Test animals
- Species:
- other: Wistar rat and guinea pig
Test system
- Type of coverage:
- occlusive
- Vehicle:
- other: Propylen glycol
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- corrosive
- Remarks:
- Migrated information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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