Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 213-697-3 | CAS number: 1003-03-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Toxicity to fish
Based on the results of a static test with the zebrafish (Danio rerio) following OECD 203, the 96h LC50 as the geometric mean value was determined to be at 197 mg/L, based on arithmetic mean concentrations of pH adjusted test solutions (BASF AG, 1998). The test was performed under GLP, the test concentrations were analytically verified and all validity criteria fulfiled. There is a geometric mean value (LC50) for non pH-adjusted test solutions at 124 mg/L but the pH effect is obvious in this case. Therefore, the substance is with high probability acutely not harmful to fish.
There is no data available on long-term effects on fish.
Toxicity to aquatic invertebrates
In a static study following EC method C.2 with Daphnia magna, the 48h EC50 (immobilization) was determined to be 52.81 mg/L based on nominal concentrations without pH adjustment (BASF AG, 1987). The non-GLP study fulfilled all validity criteria, there was no analytical monitoring during the test. Using the EC50 value, cyclopentylamine is acutely harmful to aquatic invertebrates. There is no data available on log-term effects on aquatic invertebrates.
Toxicity to aquatic algae
In a static study following OECD 201 with Desmodesmus subspicatus, the 72h ErC50 was determined to be 87.4 mg/L (ErC10 = 40.9 mg/L) based on nominal concentrations (BASF AG, 1987) without pH adjustment. The non-GLP study does not fulfill all recent validity criteria. The mean specific growth rate, which is used for the EC50/EC10 and the hazard assessment fulfilled the validity criteria. Therefore, the test can be used for the assessment. There was no analytical monitoring during the test. Based on the EC50 value, cyclopentylamine is acutely harmful to algae.
Toxicity to microorganisms
There is a growth inhibtion test with Pseudomonas putida according to Bringmann-Kuehn available. The 17h EC10 was determined to be 68.3 mg/L (BASF AG, 1987). This test is used deriving the PNEC STP since the short-term respiration test (similar to OECD 209) was performed with activated industrial sludge (and not domestic), the 30min EC20 of >663 mg/L (BASF AG, 1988) could not be used for the PNEC assessment. However, since the EC20 on acitivated sludge is higher than the highest tested concentration, the inhibition of the degradation activity of activated sludge in wwtps is not likely when cyclopentylamine is introduced in appropriately low concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.