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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Given the precision required (the solubility is determined as a range), no sufficient human error is expected which could lead to a non reliable result

Data source

Reference
Reference Type:
other: Company data
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
1-Tared a dried volumetric flask at a fixed temperature of 20°C.
2-Fill in the flask with 100mg of the substance
3-Add 0.1ml of water and check if the sustance is miscible: if not go to step 4)
4-Add 0.9mL of water and check if the sustance is miscible: if not go to step 5)
5-Add 2mL of water and check if the sustance is miscible: if not go to step 6)
6-Add 7mL of water and check if the sustance is miscible: if not go to step 7)
7-Tared a dried volumetric flask at a fixed temperature of 20°C.
Fill in the flask with 10mg of the substance, add 10mL of water and check if the sustance is miscible: if not go
to step 8)
8-Tared a dried volumetric flask at a fixed temperature of 20°C.
Fill in the flask with 1mg of the substance, add 10mL of water and check if the sustance is miscible : if not the
substance is not miscible in water.
GLP compliance:
yes
Type of method:
other: European Pharmacopoeia

Test material

Constituent 1
Chemical structure
Reference substance name:
N-benzyl-2-bromo-3-methoxypropanamide
EC Number:
700-538-2
Cas Number:
705283-58-5
Molecular formula:
C11H14BrNO2
IUPAC Name:
N-benzyl-2-bromo-3-methoxypropanamide

Results and discussion

Water solubility
Water solubility:
< 0.1 g/L
Temp.:
20 °C
Details on results:
1mg of the substance is not miscible in 10mL of water at 20°C : not soluble.
Note : given the poor hydrosolubility, determination of the pH has no sense.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): other: <0.1g/L
At 20°C, the substance is insoluble in water according to European Pharmacopoeia.