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Diss Factsheets
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EC number: 215-608-3 | CAS number: 1333-83-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.9 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- no data: aquatic toxicity unlikely
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 51 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 3.52 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 11 mg/kg soil dw
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Available studies were performed with sodium fluoride (NaF); read-across is appropriate as both NaF and sodium hydrogen difluoride are highly water soluble and therefore will dissociate into their constituent ions in the aquatic environment. The same is true for hydrogen fluoride (HF) for which data is available from the HF EU RAR. The toxicity of these substances is essentially due to the fluoride ion. The EU RAR notes a clear relationship between the aquatic toxicity of sodium fluoride (and therefore its dissociated fluoride) and water hardness. Tests performed in soft water (<50 mg CaCO3/L) showed greater toxicity than those performed in hard water (>50 mg CaCO3/L) due to the precipitation of fluoride as CaF2. All endpoints are expressed in terms of concentrations of the fluoride ion (F-).
As such all PNECs above are derived in terms of the fluoride ion in a read across approach HF and to NaF. This is considered valid in all cases for sodium hydrogendifluoride.
The derived sodium fluoride/fluoride ion PNECs are presented below:
PNEC Aqua (freshwater) - The aquatic PNEC is derived from the arithmetic mean NOEC of 8.9 mg/L from the long-term studies in Daphnia; the lowest EC50 value for Scenedesmus of 43 mg/L is also taken into consideration. However it is noted that the natural background levels of fluoride in water are variable, therefore the PNEC is not directly applicable to those areas with high natural background levels. The EU RAR suggests that the background concentration should be added to the PNEC for the purposes of risk characterisation. Although a lower NOEC of 4 mg/L is available from a fish study, this is not considered appropriate for the PNEC derivation as the test was performed in very soft water. Based on an assessment factor of 10, the PNEC is 0.9 mg/L.
PNEC Aqua (marine water) - A separate PNEC for marine waters is not derived; the freshwater PNEC is considered to be adequately protective. Background levels of fluoride are higher in seawater than in freshwater and are higher that the PNEC of 0.9 mg/L.
PNEC Aqua (intermittent releases) - A separate PNEC for intermittent release is not derived.
PNEC Sediment - In the absence of any ecotoxicological data for freshwater sediment dwelling organisms, a provisional PNECsediment is derived by calculation with the equilibrium partitioning method (EPM) on the basis of the outcome of the aquatic toxicity data according to the calculations specified in the REACH guidance document chapter R 10. For PNEC derivation the physicochemical properties of hydrogen fluoride are taken into account. As discussed in section 4 the behaviour of hydrogen fluoride in the environment is complex and as such the EPM PNEC values have been calculated based on the estimated Kow and Koc values as used in environmental modelling. A PNECsediment of 0.766 mg/kg wwt is obtained. This value may be converted from wet-weight to dry weight using a conversion factor for sediment concentrations of 4.6.
PNEC terrestrial - PNEC soil is based on the lowest NOEC of 106 mg/kg for nitrification; a factor of 10 is used as data are available for three trophic levels.
PNEC STP - The PNEC STP is based on the NOEC of 510 mg/L from a guideline-compliant activated sludge test.
No PNECs for other compartments (for example air) are considered necessary.
Conclusion on classification
No classification is triggered based on available data, according to EEC Council Directive 79/831/EEC Annex VI, Part II (D) as described in Commission Directive 93/21/EEC or Regulation (EC) No 1272/2008. No hazards for the environment have been identified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.