Registration Dossier
Registration Dossier
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EC number: 204-820-1 | CAS number: 127-06-0
Endpoint summary
Administrative data
Description of key information
Additional information
A reliable measured biodegradation study in water for acetone oxime is available and included in the dossier. Reliable studies on the biodegradation in sediment and soil are not available, however a waiver is applied for these endpoints.
A reliable (Klimisch 1) biodegradation study has been conducted for acetone oxime and is included in this dossier. The key study, Bayless (2012), determined that acetone oxime is not readily biodegradable. Consequently this study will be taken for the biodegradation in water endpoint.
Waiver. In accordance with Column 2 of REACH Annex IX, the simulation test on ultimate degradation in surface water, the soil simulation test and the sediment simulation test (required in Sections 9.2.1.2, 9.2.1.3 and 9.2.1.4 respectively) do not need to be conducted asdirect or indirect exposure of surface water, soil and sediment is unlikely.The chemical safety assessment does not indicate any need to investigate further the degradation of the substance and its degradation products. Also, the substance’s low hydrophilicity is demonstrated by the very low log octanol-water partition coefficient (Log Kow) of 0.077 at a neutral pH and low Koc (0.517) indicating low adsorptive potential. Therefore, no additional degradation testing is necessary based on unlikely exposure. Identification of degradation products (required in Section 9.2.3) is also not necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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