Registration Dossier
Registration Dossier
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EC number: 207-988-4 | CAS number: 504-29-0
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Not known
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data obtained from an authoritative secondary source
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Aminopyridines
- Year:
- 2 005
- Bibliographic source:
- http://www.epa.gov/hsrb/files/meeting-materials/jun-27-29-2007-public-meeting/nci-2006.pdf
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- No other information available from data source
- GLP compliance:
- not specified
- Remarks:
- No other information available from data source
- Type of study:
- other: Buehler Topical Closed Patch Skin Sensitization Test
Test material
- Reference substance name:
- 2-pyridylamine
- EC Number:
- 207-988-4
- EC Name:
- 2-pyridylamine
- Cas Number:
- 504-29-0
- Molecular formula:
- C5H6N2
- IUPAC Name:
- pyridin-2-amine
Constituent 1
In vivo test system
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
Results and discussion
Any other information on results incl. tables
No other information available from data source
Applicant's summary and conclusion
- Conclusions:
- 2-Aminopyridine lacked skin sensitization in the Buehler Topical Closed Patch Skin Sensitization Test; testing per DOT protocol showed 2-aminopyridine to be negative for corrosivity
- Executive summary:
2-Aminopyridine lacked skin sensitization in the Buehler Topical Closed Patch Skin Sensitization Test; testing per DOT protocol showed 2-aminopyridine to be negative for corrosivity.
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