Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 469-110-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The Daphnia magna 48h-EC50 exceeded an average measured concentration of 4 µg/l, which was above the water solubility limit of < 0.7 µg/l.
Key value for chemical safety assessment
Additional information
A combined limit/range-finding test was performed with
twenty daphnia per test group (4 vessels with 5 daphnia
each) exposed to a control and a WAF prepared at 100 mg/l in
the limit test and ten daphnia per test group (2 vessels
with 5 daphnia each) exposed to WAFs prepared at 1.0 and 10
mg/l in the combined range-finding test. The total test
period was 48 hours and samples for analytical confirmation
of actual exposure concentrations were taken at the start
and the end of the test.
Mean recoveries of the procedural recovery samples were 57%
and 47%. These relatively low recoveries were probably
caused by the poor solubility of the test substance.
Analysis of the samples taken from the WAF prepared at a
loading rate of 100 mg/l showed that the measured
concentration decreased from 5 µg/l at the start to 3 µg/l
after 48 hours of exposure. The average concentration was
calculated to be 4 µg/l. This concentration was a factor of
at least 5 higher than the water solubility, which was
determined to be less than 0.7 µg/l (see
water solubility).
Under the conditions of the present study AD-1000 did not induce acute immobilisation of Daphnia magna at or below a Water Accommodated Fraction prepared at a loading rate of 100 mg/l, which corresponded to an average measured concentration of 4 µg/l (NOEC). Hence, the 48h-EC50 exceeded an average measured concentration of 4 µg/l, which was above the water solubility limit of < 0.7 µg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.