Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Read across based on structural similarity
- Justification for type of information:
- Read across to Sarolaner step 2
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.27 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.27 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- yield
- Conclusions:
- Under the conditions of the present study, no significant inhibition of growth rate was recorded at any of the concentrations tested.
Both the EC50 for growth rate inhibition (72h-ErC50) and the EC50 for yield inhibition (72h-EyC50)
exceeded 0.27 mg/l, being the TWA concentration measured in a 0.45 μm filtered solution prepared at a loading rate of 100 mg/l.
Reference
Description of key information
Read across from Sarolaner API:
Both the EC50 for growth rate inhibition (72h-ErC50) and the EC50 for yield inhibition (72h-EyC50) exceeded 0.27 mg/l, being the TWA concentration measured in a 0.45 μm filtered solution prepared at a loading rate of 100 mg/l.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.27 mg/L
- EC10 or NOEC for freshwater algae:
- 0.27 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
