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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

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Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Qualifier:
according to guideline
Guideline:
other: section 63-8 40 CFR 158.190.
Deviations:
no
GLP compliance:
yes
Specific details on test material used for the study:
XRD-535 ME
Lot # AGR 259823
Purity: 98.6%
Key result
Medium:
acetone
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
other: Aromatic 100
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
other: cyclohexanone
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
other: dichloromethane
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
dimethylformamide
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
ethanol
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
ethyl acetate
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
other: hexane
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
isopropanol
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
methanol
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
toluene
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Key result
Medium:
other: xylene
Temp.:
20 °C
Remarks on result:
other: Miscible at 50% w/w
Conclusions:
The test substance was found to be miscible in all solvents including acetone, aromatic 100, cyclohexanone, dichloromethane, dimethylformamide, ethanol, ethyl acetate, hexane, isopropanol, methanol, toluene, and xylene.
Executive summary:

The solubility of the test substance was determined in 12 organic solvents. The test substance was found to be miscible in all solvents including acetone, aromatic 100, cyclohexanone, dichloromethane, dimethylformamide, ethanol, ethyl acetate, hexane, isopropanol, methanol, toluene, and xylene.

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Deviations:
no
GLP compliance:
no
Specific details on test material used for the study:
Haloxyfop (XRD-535) Methylester
Lot # GHD-2266-15
Purity: Not reported
Key result
Medium:
other: fat simulant HB 307
Temp.:
37 °C
Remarks on result:
other: uniform and homogeneous solution was formed
Conclusions:
The test sample is soluble in fat in each ratio
Executive summary:

The fat solubility of the test substance at 310 K (37 °C) was determined according to the OECD-Guideline No. 116. A fat simulant HB 307 was used as solvent and the concentration of the test substance in the saturated solution has to be determined.

From preliminary tests it was found, that the test sample is soluble in fat in each ratio. Therefore the main test and an analytical determination of the equilibrium concentration of the test sample in fat is not logical.

Description of key information

OECD 116

Key value for chemical safety assessment

Additional information

The test substance was found to be miscible in all solvents including acetone, aromatic 100, cyclohexanone, dichloromethane, dimethylformamide, ethanol, ethyl acetate, hexane, isopropanol, methanol, toluene, and xylene