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EC number: 814-072-3 | CAS number: 77614-79-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2018 - May 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Version / remarks:
- 2000
- Qualifier:
- according to guideline
- Guideline:
- other: Commission Regulation (EU) No 283/2013 in accordance with Regulation (EC) No 1107/2009
- Version / remarks:
- 2013
- Qualifier:
- according to guideline
- Guideline:
- other: US EPA OCSPP Guideline No. 835.1230
- Version / remarks:
- 2008
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- batch equilibrium method
- Media:
- soil
Test material
- Reference substance name:
- 3,5-bis(difluoromethyl)-1H-pyrazole
- EC Number:
- 814-072-3
- Cas Number:
- 77614-79-0
- Molecular formula:
- C5H4F4N2
- IUPAC Name:
- 3,5-bis(difluoromethyl)-1H-pyrazole
Constituent 1
- Radiolabelling:
- yes
Study design
- Test temperature:
- 19.68 - 20.18 °C
Batch equilibrium or other method
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: Nominal test item concentrations of 2.0, 1.0, 0.2, 0.1 and 0.02 mg/L
- Sampling interval: 6, 24 and 48 h
- Sample storage before analysis: Stabilized supernatant and soil extracts were stored at <= -18 °C in the dark for 7 days .
Matrix propertiesopen allclose all
- Matrix no.:
- #1
- Matrix type:
- loamy sand
- % Clay:
- 6
- % Silt:
- 16
- % Sand:
- 78
- % Org. carbon:
- 1.5
- pH:
- 5.4
- CEC:
- 7.6 meq/100 g soil d.w.
- Bulk density (g/cm³):
- 1.21
- Matrix no.:
- #2
- Matrix type:
- clay loam
- % Clay:
- 28
- % Silt:
- 38
- % Sand:
- 34
- % Org. carbon:
- 4.9
- pH:
- 7.3
- CEC:
- 18.7 meq/100 g soil d.w.
- Bulk density (g/cm³):
- 0.98
- Matrix no.:
- #3
- Matrix type:
- silt loam
- % Clay:
- 16
- % Silt:
- 58
- % Sand:
- 26
- % Org. carbon:
- 1.8
- pH:
- 6
- CEC:
- 10.7 meq/100 g soil d.w.
- Bulk density (g/cm³):
- 1.11
- Matrix no.:
- #4
- Matrix type:
- silt loam
- % Clay:
- 16
- % Silt:
- 56
- % Sand:
- 28
- % Org. carbon:
- 2.6
- pH:
- 5.2
- CEC:
- 10 meq/100 g soil d.w.
- Bulk density (g/cm³):
- 0.99
- Matrix no.:
- #5
- Matrix type:
- sandy loam
- % Clay:
- 11.5
- % Silt:
- 33.1
- % Sand:
- 55.4
- % Org. carbon:
- 1.06
- pH:
- 7.3
- CEC:
- 4.2 meq/100 g soil d.w.
- Bulk density (g/cm³):
- 1.167
- Details on matrix:
- IDENTIFICATION
Soil ID and Geographic location:
#1 - AX - Monheim, Germany
#2 - DD - Blankenheim, Germany
#3 - HH - Burscheid, Germany
#4 - HN - Bruscheid, Germany
#5 - 5M - Mechtersheim, Germany
COLLECTION AND STORAGE
- Sampling depth (cm): 0 - 20 cm
- Storage conditions: romm temperature
- Storage length: max. 2.5 years
- Soil preparation (e.g.: 2 mm sieved; air dried etc.): 2 mm sieved and air dried after collection, sterlizied via gamma ray treatment prior use
- Details on test conditions:
- TEST CONDITIONS
- Buffer:aqueous 0.01 M CaCl2 solution
- pH: aqueous 0.01 M CaCl2 solution without soil: 6.73
- Shaking conditions approx. 150rpm
- Light conditions: dark
TEST SYSTEM
- Type, size and further details on reaction vessel: Glass flasks with screw caps
- Water filtered (i.e. yes/no; type of size of filter used, if any): no
- Amount of soil/sediment/sludge and water per treatment (if simulation test): 10 g dry weight equivalents per replicate
- Soil/sediment/sludge-water ratio (if simulation test): 1/1 , 1/2, 1/5
- Number of reaction vessels/concentration: 2
- Test performed in closed vessels due to significant volatility of test substance: closed vessel
- Method of preparation of test solution:245 µL stock solution was dissolved in 4255 µL acetonitrile/water (10/90, v/v) resulting in an application solution with a concentration of 0.84 MBq/mL (equal to 210.606 mg/L using a specific activity of 3.99 MBq/mg) - Are the residues from the adsorption phase used for desorption: No
Duration of adsorption equilibrationopen allclose all
- Sample No.:
- #1
- Duration:
- 24 h
- Remarks:
- AX
- Sample No.:
- #2
- Duration:
- 24 h
- Remarks:
- DD
- Sample No.:
- #3
- Duration:
- 24 h
- Remarks:
- HH
- Sample No.:
- #4
- Duration:
- 24 h
- Remarks:
- HN
- Sample No.:
- #5
- Duration:
- 6 h
- Remarks:
- 5M
Results and discussion
Adsorption coefficientopen allclose all
- Sample No.:
- #1
- Type:
- Koc
- Value:
- 9.4 L/kg
- pH:
- 5.4
- Temp.:
- 19.68 °C
- Matrix:
- loamy sand
- % Org. carbon:
- 1.5
- Remarks on result:
- other: Matrix #1
- Sample No.:
- #2
- Type:
- Koc
- Value:
- 7.5 L/kg
- pH:
- 7.3
- Temp.:
- 19.68 °C
- Matrix:
- clay loam
- % Org. carbon:
- 4.9
- Remarks on result:
- other: Matrix #2
- Sample No.:
- #3
- Type:
- Koc
- Value:
- 9.2 L/kg
- pH:
- 6
- Temp.:
- 19.68 °C
- Matrix:
- silt loam
- % Org. carbon:
- 1.8
- Remarks on result:
- other: Matrix #3
- Sample No.:
- #4
- Type:
- Koc
- Value:
- 10.9 L/kg
- pH:
- 5.2
- Temp.:
- 19.68 °C
- Matrix:
- silt loam
- % Org. carbon:
- 2.6
- Remarks on result:
- other: Matrix #4
- Sample No.:
- #5
- Type:
- Koc
- Value:
- 7.5 L/kg
- pH:
- 7.3
- Temp.:
- 19.68 °C
- Matrix:
- sandy loam
- % Org. carbon:
- 1.06
- Remarks on result:
- other: Matrix #5
- Sample No.:
- #1
- Type:
- other: Kfoc
- Value:
- 9 L/kg
- pH:
- 5.4
- Temp.:
- 19.68 °C
- Matrix:
- loamy sand
- % Org. carbon:
- 1.5
- Remarks on result:
- other: Matrix #1
- Sample No.:
- #2
- Type:
- other: Kfoc
- Value:
- 8.3 L/kg
- pH:
- 7.3
- Temp.:
- 19.68 °C
- Matrix:
- clay loam
- % Org. carbon:
- 4.9
- Remarks on result:
- other: Matrix #2
- Sample No.:
- #3
- Type:
- other: Kfoc
- Value:
- 9.4 L/kg
- pH:
- 6
- Temp.:
- 19.68 °C
- Matrix:
- silt loam
- % Org. carbon:
- 1.8
- Remarks on result:
- other: Matrix #3
- Sample No.:
- #4
- Type:
- other: Kfoc
- Value:
- 13.6 L/kg
- pH:
- 5.2
- Temp.:
- 19.68 °C
- Matrix:
- silt loam
- % Org. carbon:
- 2.6
- Remarks on result:
- other: Matrix #4
- Sample No.:
- #5
- Type:
- other: Kfoc
- Value:
- 6.7 L/kg
- pH:
- 7.3
- Temp.:
- 19.68 °C
- Matrix:
- sandy loam
- % Org. carbon:
- 1.06
- Remarks on result:
- other: Matrix #5
Results: Batch equilibrium or other method
Mass balance (%) at end of adsorption phaseopen allclose all
- Sample no.:
- #1
- Duration:
- 24 h
- % Adsorption:
- 98.6
- Sample no.:
- #2
- Duration:
- 24 h
- % Adsorption:
- 100
- Remarks on result:
- other: 101.4 %
- Sample no.:
- #3
- Duration:
- 24 h
- % Adsorption:
- 99.3
- Sample no.:
- #4
- Duration:
- 24 h
- % Adsorption:
- 96.4
- Sample no.:
- #5
- Duration:
- 6 h
- % Adsorption:
- 100
- Remarks on result:
- other: 100.2 %
- Transformation products:
- no
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The adsorption constants KF of the test item for the tested soils calculated based on the Freundlich isotherms ranged 0.0715 to 0.4057 mL/g (arithmetic mean: 0.2273 mL/g). The respective KFoc values ranged from 6.7 to 13.6 mL/g (arithmetic mean: 9.4 mL/g).
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