Registration Dossier
Registration Dossier
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EC number: 947-879-5 | CAS number: 2475232-73-4
Surface tension
Administrative data
- Endpoint:
- surface tension
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 115 (Surface Tension of Aqueous Solutions)
- Version / remarks:
- 27 July 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- ring method
Test material
- Reference substance name:
- 4-[3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
- Molecular formula:
- C23H18Cl2F4N2O4
- IUPAC Name:
- 4-[3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
- Test material form:
- solid
- Details on test material:
- Off-white
Constituent 1
Results and discussion
Surface tension
- Key result
- Surface tension:
- 71.1 mN/m
- Temp.:
- 20 °C
- Conc.:
- 90 other: % saturated solution
Applicant's summary and conclusion
- Conclusions:
- The average surface tension of duplicate 90% saturated solutions of test substance in water was 71.1 mN/m at 20 °C.
- Executive summary:
The surface tension of duplicate 90% saturated solution of the test substance in high purity water was determined under GLP to OECD TG 115, using the ring method. A proper aliquot of test substance was diluted in high purity water (with a specification of resistance >18.2 MΩ and TOC <5 ppb). Duplicate sample solutions were prepared for two independent determinations by diluting an aliquot of about 0.1 g of test substance in 200 mL high purity water. This solution was then shaken at 30 °C for about 24 hours. The solution was then equilibrated at 20 °C for about 16.5 hours. The saturated solution was then centrifuged at 13000 rpm for 15 minutes and filtered through 0.22 μm filters. The isolated, saturated filtrate ws then diluted to 90% of its former concentration with high purity water. The sample solution was then transferred to the measuring vessel. The measurements for done with a torsion balance for surface and interfacial tension determinations. The measured surface tension values of the 90% saturated solutions were 71.2 mN/m and 71.0 mN/m, resulting a mean surface tension of 71.1 mN/m at 20.0 ± 0.5 °C. The pH value of the two solutions was 6.0.
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