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EC number: 951-929-1 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2020-04-14 to 2020-08-06
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Batch: 2018060002
pH: 7.60
moisture content: 30.29% - Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- > 4
- Temp.:
- 20 °C
- Remarks on result:
- other: In total, 66 % of the total peak area of the test item was attributed to a log POW of ≥ 6.0
- Details on results:
- The test item RICOIL EN is a UVCB substance, consisting of multiple constituents. The partition coefficients at 20 °C of the individual components of the test item RICOIL EN were determined by means of the HPLC method, according to Regulation (EC) No 440/2008 Method A.8. and OECD Test Guideline 117 (2004) to be:
Component 1: not assignable
Component 2: not assignable
Component 3: not assignable
Component 4: log POW < 1.0
Component 5: log POW = 6.0
Component 6: log POW = 6.2
Component 7: log POW > 6.5
In total, 66 % of the total peak area of the test item was attributed to a log POW of ≥ 6.0. The results from the HPLC method agree with the results of the preliminary test in which the log POW of the test item was estimated to be > 4.0 on the basis of the water solubility of the test item and the solubility of the test item in 1-octanol. - Conclusions:
- The test item RICOIL EN is a UVCB substance, consisting of multiple constituents. The partition coefficients at 20 °C of the individual components of the test item RICOIL EN were determined by means of the HPLC method, according to Regulation (EC) No 440/2008 Method A.8. and OECD Test Guideline 117 (2004) to be:
Component 1: not assignable
Component 2: not assignable
Component 3: not assignable
Component 4: log POW < 1.0
Component 5: log POW = 6.0
Component 6: log POW = 6.2
Component 7: log POW > 6.5
In total, 66 % of the total peak area of the test item was attributed to a log POW of ≥ 6.0. The results from the HPLC method agree with the results of the preliminary test in which the log POW of the test item was estimated to be > 4.0 on the basis of the water solubility of the test item and the solubility of the test item in 1-octanol. - Executive summary:
The test item RICOIL EN is a UVCB substance, consisting of multiple constituents. The partition coefficients at 20 °C of the individual components of the test item RICOIL EN were determined by means of the HPLC method, according to Regulation (EC) No 440/2008 Method A.8. and OECD Test Guideline 117 (2004) to be:
Component 1: not assignable
Component 2: not assignable
Component 3: not assignable
Component 4: log POW < 1.0
Component 5: log POW = 6.0
Component 6: log POW = 6.2
Component 7: log POW > 6.5
In total, 66 % of the total peak area of the test item was attributed to a log POW of ≥ 6.0. The results from the HPLC method agree with the results of the preliminary test in which the log POW of the test item was estimated to be > 4.0 on the basis of the water solubility of the test item and the solubility of the test item in 1-octanol.
Reference
Description of key information
The test item RICOIL EN is a UVCB substance, consisting of multiple constituents. The partition coefficients at 20 °C of the individual components of the test item RICOIL EN were determined by means of the HPLC method, according to Regulation (EC) No 440/2008 Method A.8. and OECD Test Guideline 117 (2004) to be:
Component 1: not assignable
Component 2: not assignable
Component 3: not assignable
Component 4: log POW < 1.0
Component 5: log POW = 6.0
Component 6: log POW = 6.2
Component 7: log POW > 6.5
In total, 66 % of the total peak area of the test item was attributed to a log POW of ≥ 6.0. The results from the HPLC method agree with the results of the preliminary test in which the log POW of the test item was estimated to be > 4.0 on the basis of the water solubility of the test item and the solubility of the test item in 1-octanol.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4
- at the temperature of:
- 20 °C
Additional information
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