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EC number: 405-520-5 | CAS number: 95235-30-6 D-8; DD-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1988-07-11 to 1988-12-24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 10
- Deviations:
- not specified
- Principles of method if other than guideline:
- The water solubility was analysed by HPLC chromatography with UV detection.
- GLP compliance:
- not specified
- Type of method:
- flask method
- Key result
- Water solubility:
- 19.7 mg/L
- Temp.:
- 25 °C
- pH:
- 6.85
- Details on results:
- The amount of D-8 is calculated based on the peak areas as follows:
Solubility (g/L) = Cs x Vs x Au x F / As x Vu
whereas
Cs : Concentration of standard solution (g/L)
Vs : Injected volume of standard solution (µL)
As : Mean of integral peak area of standard
Vu : Injected volume of sample solution (µL)
Au : Mean of integral peak area of the sample
F : Concentration/dilution factor - Conclusions:
- The solubility of D-8 in distilled water was determined according to the method CIPAC MT 10. The solubility of D-8 in distilled water was 19.7 mg/L at a pH of 6.85 and 25 °C.
- Executive summary:
The solubility of D-8 in distilled water was determined according to the method CIPAC MT 10. About 3 mg of D-8 was weighed into each of six medium bottles and 50 mL of distilled water was added to each flask. They wre stoppered and immersed in an ultrasonic bath for 15 min below 30 °C. They were shaken at about 150 frequencies/min by a mechanical shaker for 40 min at 25 °C.
The flasks were kept at 25 °C for 0, 24 and 168 hours. The two of them were separately filtered through a membrane fliter (0.45.µm) under reduced pressure. About 10 mL of the initial filtrate was discarded. The rest of the filtrate was measured for pH, and 10 mL of the filtrate was pipetted into the 20 or 25 mL volumetric flask and diluted with methanol. An aliquot (10 µL) of the solution was duplicately injected into the HPLC and the amount of D-8 was calculated.
The solubility for D-8 in distilled water was 19.7 mg/L at a pH of 6.85 and 25 °C.
Reference
The pH of the filtrate was 6.85. The solubility of D-8 increased with the time as showed in the table.
At the longest saturation time of 168 hours, the mean value was 19.7E-3 g/L at 25 °C.
Table: Solubility of D-8 in Water.
Saturation time (hrs) |
0 |
24 |
168 |
Solubility |
1 * 2 15.25 |
18.49 16.92 |
19.15 20.14 |
(x 10-3 g/L) |
Av. 15.66 |
17.71 |
19.65 |
* Figures are mean values of 2 measurements
Description of key information
The solubility of D-8 in distilled water was 19.7 mg/L at a pH of 6.85 and 25 °C, as determined according to the method CIPAC MT 10.
Key value for chemical safety assessment
- Water solubility:
- 19.7 mg/L
- at the temperature of:
- 25 °C
Additional information
The solubility of D-8 in distilled water was determined according to the method CIPAC MT 10. The solubility of D-8 in distilled water was 19.7 mg/L at a pH of 6.85 and 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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