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Diss Factsheets
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EC number: 819-688-6 | CAS number: 219828-90-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06 Dec 2013 - 30 Jan 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations:
range finding test - 1, 10, 100 mg/L,
main test - 1, 1.8, 3.2, 5.6, 10mg/L
- Sampling method: one set of new sample solution at time of preparation and one at end of exposure.
- Sample storage conditions before analysis: frozen - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
The test solutions, approximately 100mL, were poured into each of the five vessels per test group and immediately plugged with a ground-in stopper to prevent volatilization of the test substance.
One of the five vessels of each test group was used for measuring the test conditions. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Source: National Institute for Environmental Studies, Japan
Growth stage: juveniles less than 24-hour old (female) - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 242 mg CaCO3/L
- Test temperature:
- 20 ± 1°C
- pH:
- 8.5
- Dissolved oxygen:
- not specified
- Salinity:
- not specified
- Conductivity:
- not specified
- Nominal and measured concentrations:
- Nnominal: 1, 1.8, 3.2, 5.6, 10 mg/L
Mean measured: 0.951, 1.55, 3.05, 5.49 and 9.87 mg/L - Details on test conditions:
- Duration: 48 hours
Exposure procedure: static,
Volume of the test solutions:100mL/vessel
Number of vessels: 4 vessels/ test group
Loading: 20 daphnids/test group (5 daphnids/vessel)
Temperature: 20 ± 1°C
pH: 6.0 - 9.0
Light: Fluorescent light, 16 hour light (800 lux or less)/ 8 hour dark
Feeding: None
RANGE-FINDING STUDY
- Test concentrations: 1, 10, 100 mg/L
- Results used to determine the conditions for the definitive study: yes - Reference substance (positive control):
- yes
- Key result
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 8.22 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3.94 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Results with reference substance (positive control):
- not specified
- Validity criteria fulfilled:
- yes
- Conclusions:
- 48 hour EC50: 3.94mg/L
48 hour EC0: 1.55mg/L
48 hour EC100: 5.49mg/L
Reference
Description of key information
Daphnia Magna 48-hour
EC50 - 3.94 mg/L
EC0 - 1.55 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 3.94 mg/L
Additional information
A determination of the acute toxicity to aquatic invertebrates of 2-(Allyloxymethyl) acrylic acid methyl ester was conducted (Mitsubishi Chemical Medience Corporation, 2014, Study A130914).
The study was performed in accordance with OECD test guideline 202, and in compliance with GLP.
Groups of 20 Daphnia magna were exposed to 0 (control group), 1.0, 1.8, 3.2, 5.6, or 10 mg/L 2-(Allyloxymethyl) acrylic acid methyl ester in Elendt M4 Culture medium.
After 24 hours' exposure, 80% Daphnia in the 10 mg/L group were immobilised but no Daphnia in other groups were immobilised. After 48 hours, all of the Daphnia in the 5.6 and 10 mg/L group and 5% of the Daphnia in the 3.2 mg/L group were immobilised, however any of the Daphnia in the lower concentration groups were immobilised.
It was concluded that the 48-hour EC50 in Daphnia Magna was 3.94 mg/L and EC0 in Daphnia Magna was 1.55 mg/L
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