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Diss Factsheets
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EC number: 204-729-7 | CAS number: 125-20-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Density
Administrative data
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- pycnometer method
Test material
- Reference substance name:
- 3,3-bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
- EC Number:
- 204-729-7
- EC Name:
- 3,3-bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
- Cas Number:
- 125-20-2
- Molecular formula:
- C28H30O4
- IUPAC Name:
- 3,3-bis(4-hydroxy-5-isopropyl-o-tolyl)phthalide
- Details on test material:
- - Storage conditions: Room Temperature (20 ± 5 °C)
- Expiry date: 16. Dec. 2019
Constituent 1
Results and discussion
Densityopen allclose all
- Type:
- density
- Density:
- 1.111 g/cm³
- Temp.:
- 20 °C
- Type:
- relative density
- Density:
- 1.111 other: unitless
- Temp.:
- 20 °C
Applicant's summary and conclusion
- Conclusions:
- The density of the test item has been determined to be 1.111 g/cm3 at 20 °C.
The study was performed according to the OECD TG109 and EU Method A.3 without deviations and therefore considered to be of the highest quality (reliability Klimisch 1). - Executive summary:
The density of the test item was determined in a study according to OECD 109 resp. EU Method A.3 (pycnometer).
All procedures involving the pycnometer from wiping with the buckskin cloth to weighing were performed wearing cotton gloves. At all weighings, the corresponding temperature was recorded. All weighings were performed at 20.0 ± 0.2 °C. The determination was performed in duplicate.
The pycnometer was meticulously cleaned and dried. Pycnometer, test item, replacement liquid and water were tempered till room temperature. The test item was ground with mortar and pestle.
The pycnometer was rinsed with the ambient air, the outside was wiped with a clean buckskin cloth. After at least 10 minutes further standing, the dead weight was recorded (M1).
In order to determine the volume of the pycnometer, it was filled with water, wiped again and, after at least 10 minutes, weighed (M2).
The (cleaned) pycnometer was filled with replacement liquid, wiped again, and, after at least 10 minutes, weighed (M3). The pycnometer was then emptied, cleaned, and dried through rinsing with acetone and aeration with filtered air. Approx. 9 g of the ground test substance were filled into the pycnometer, the weight was recorded (M4). Then, replacement liquid was added to the mark and the pycnometer was weighed again (M5).
Before recording of the final weight, the pycnometer was set into an ultrasonic bath in order to remove any bubbles.
A density of 1.1110 ± 0.0011 g/cm3 at 20.0 ± 0.2 °C was measured. This value is the mean of two independent determinations with the maxi-mum error of a single determination. Standard deviation was 0.0011 g/cm3, showing good correlation of the two determinations. Therefore, the study is considered valid.
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