Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
other: collection of data
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Toxicology of the Eye
Author:
Grant, W.M.
Year:
1986
Bibliographic source:
Grant, W.M. Toxicology of the Eye. 3rd ed. Springfield, IL: Charles C. Thomas Publisher, 1986
Reference Type:
other: collection of data
Title:
Query: Records containing the term 1-OCTANOL as displayed on http://toxnet.nlm.nih.gov on December 18, 2018.
Author:
Hazardous Substances Data Bank (HSDB)

Materials and methods

GLP compliance:
not specified

Test material

Test material form:
liquid

Results and discussion

Any other information on results incl. tables

Octanol ... has caused transient injury of corneal epithelium, with recovery in 48 hr.

Applicant's summary and conclusion

Interpretation of results:
Category 2 (irritating to eyes) based on GHS criteria