Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-894-2 | CAS number: 111-67-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non-GLP, non guideline, avalable as unpublished report, acceptable with restrictions
- Justification for type of information:
- Read-across between the target substance Oct-2-ene (EC 203-894-2 / CAS 111-67-1) and source substance 1-Tetradecene (EC 214-306-9/ CAS 1120-36-1) is based upon the similarity of the chemical structures and their respective physico-chemical properties. The ECHA Read-Across Assessment Framework (RAAF) states that substances with qualitatively similar properties can form the basis of read-across in circumstances where the source and target substances share such similar characteristics.
Target substance Oct-2-ene and source substance 1-Tetradecene are each mono-constituent linear olefins. Structurally, the differences between source and target substances include: 1) the length of the carbon chain (eight for the target substance, and fourteen for the source substance); and 2) the location of the carbon-carbon double bond (uniformly at the C2 position for the target substance, but uniformly at the C1 terminal position for the source substance).
The target and source substances both fit within the boundaries of chemical category of higher olefins. Studies conducted by the HOPA consortium on a large range of higher olefin category members (including 1-Tetradecene) demonstrated sufficiently similar physico-chemical, environmental fate and toxicological properties to substantiate the basis for read-across; although category members of a carbon chain length C10 or greater may exhibit a reduced acute aquatic toxicity attributable to reduced water solubility, the environmental toxicity of all category member is expected to be manifested as non-polar narcosis. In addition, both 1-Tetradecene and Oct-2-ene are expected to exhibit sufficient adsorption to soil and sediment to exhibit similar long-term toxicity; therefore, read-across with respect to sediment and terrestrial toxicity endpoints is appropriate. Justification for inclusion of Oct-2-ene within the boundaries of the higher olefins category, and the relevance of each category member as an analogue substance to Oct-2-ene, is provided in Section 13 (Document name: “HOPA Higher Olefins CJD with Category Matrix Report [rev 1 Sept 2016]”; Document name: "ACC Product Stewardship Summary for Higher Olefins Category (2008-12-03)”).
- Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- The acute toxicity of the test substance to barley was tested in a laboratory bioassay. Natural soil exposed in the field to the test substance was sampled over time. The bulk sample was analysed for physico chemical parameters and the concentration of the test substance. Barley was exposed to the soil samples and the effects on shoot and root length and weight recorded. Effects on barley grown in the field are also reported.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data reported - Analytical monitoring:
- yes
- Details on sampling:
- A natural silty loam soil was dosed with drill cuttings containing the test substance in September 2001. Soil samples were taken after 2.5, 7, 8 and 10.5 months. 15 soil samples from 0-15cm depth were taken on each occassion, spread evenly across the test and control plots. The samples were bulked and homogenised.
- Vehicle:
- no
- Details on preparation and application of test substrate:
- Soil samples collected in the field determined the test concentrations. The bulk soil samples had measured corrected concentrations of 31428, 25195, 8145 and 10026ug/g dry weight over time.
- Species:
- Hordeum vulgare
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- Seeds used
- Test type:
- other: shoot and root elongation, shoot and root mass
- Study type:
- laboratory study
- Substrate type:
- natural soil
- Limit test:
- no
- Total exposure duration:
- 14 d
- Post exposure observation period:
- none
- Test temperature:
- 23-28°C
- pH:
- 6.5-7.7
- Moisture:
- remoistened
- Details on test conditions:
- Photoperiod - 16L:8D. three replicates of 500cc of remoistened soil were weighed out and placed in a plastic cup. Five healthy, unblemised barley seeds were planted in the cups at a depth of approximately twice the diameter of the seed. After covering the seed, the soil surface was sprayed with deionised water and each cup was placed in an inflated plastic bag. After 14 days growth, emergence, shoot and root elongation and mass were determined. Each plant that had emerged at least 3mm above the soil surface was separated from the soil and washed free of soil. Shoot and root lengths were determined by measuring from the shoot/root interface to the tip of the longest root or shoot. Shoots and roots were separated and dried at 80°C for 48 hours before weighing.
- Nominal and measured concentrations:
- control and 31428, 25195, 8145 and 10026ug/g dry weight (measured)
- Reference substance (positive control):
- no
- Species:
- Hordeum vulgare
- Duration:
- 14 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 25 195 other: µg/g dry weight
- Nominal / measured:
- meas. (TWA)
- Conc. based on:
- test mat.
- Basis for effect:
- other: shoot length and mass
- Species:
- Hordeum vulgare
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 026 other: µg/g dry weight
- Nominal / measured:
- meas. (TWA)
- Conc. based on:
- test mat.
- Basis for effect:
- other: shoot length and mass
- Species:
- Hordeum vulgare
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 31 428 other: µg/g dry weight
- Nominal / measured:
- meas. (TWA)
- Conc. based on:
- test mat.
- Basis for effect:
- other: root length and mass
- Details on results:
- No effects seen on root length or mass. The authors note that barley plants grown in the field on the exposed soil showed no effects on growth at 10026ug/g but were extremely inhibited at 25195ug/g dry weight.
- Results with reference substance (positive control):
- not applicable
- Reported statistics and error estimates:
- No data reported
- Validity criteria fulfilled:
- no
- Remarks:
- Non standard test
- Conclusions:
- The 14 day NOEC shoot growth was 10026ug/g and the LOEC 25195ug/g for barley.
- Executive summary:
The 14 day NOEC shoot growth was 10026ug/g and the LOEC 25195ug/g for barley. Although this test does not follow standard guidelines it is well described and includes analytical monitoring of the exposure concentrations.
Reference
Description of key information
The key study was a short-term toxicity test on the effects of an analog substance on barley, Hordeum vulgare, following a non-guideline test (Visser, 2003). The 14-d NOEC was reported as 10,026 ug/g d.w.(measured) and the LOEC was reported as 25,195 ug/g d.w.(measured), each based on based on shoot length and mass. A value for EC50 was not reported.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.