Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reason / purpose for cross-reference:
- read-across source
- Conductivity:
- Not measured
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- No acute toxic effects of exposure were observed throughout the test.
No remarkable observations were made concerning the apperance of the test medium. The test medium was a clear solution throughtout the whole test duration. - Results with reference substance (positive control):
- None
- Reported statistics and error estimates:
- Not applicable.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity of FAT 41039/A, structural analogue of FAT 41048, to the freshwater invertebrate Daphnia magna was investigated and gave a 48-Hour EC50 value of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L.
- Executive summary:
The acute toxicity of FAT 41039/A, structural analogue of FAT 41048, to Daphnia magna was determined in a 48 hour static test according to the EU Commission Directive 92/69/EEC, Part C.2 (1992) and the OECD Guideline for Testing of Chemcials No. 202 (2004).
In order to assess the toxicity of the test item FAT 41039/A containing different components to Daphnia magna, a water accommodated fraction (WAF) was prepared. The method is based on the Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures (2000).
A limit test was performed in accordance the test guidelines to demonstrate that WAFs of the test item has no toxic effect on the test daphnids up the loading rate of 100 mg/L.
Before to the start of the test and prior to each test medium renewal, the test medium was prepared as follows: A dispersion of the test item with the loading rate of 100 mg/L was prepared using ultrasonic treatment and intense stirring. The dispersion was stirred at room temperature in the dark over 96 hours to dissolve a maximum amount of the different components of the test item in the test water. After the stirring period, the dispersion was filtered (0.45 µm membrane filter) and the filtrate was tested on the test fish as WAF. Additionally, a control was tested in parallel.
The analytically measured test item concentration in the WAF with the loading rate of 100 mg/L was below the limit of quantification of the analytical method of 0.3 µg/L at the start and the end of the test. The biological results were based on the loading rate of the WAF of 100 mg/L.
In the control and at the loading rate of 100 mg/L, no mortality or other visible abnormalities were determined during the test period of 96 hours.
The 48-hour NOEC (highest concentration tested without toxic effects after the exposure period of 48 hours) and the 48-hour EC0 of FAT 41039/A to Daphnia magna were determined to be the loading rate of at least 100 mg/L. The 48-hour NOEC and the 48-hour EC0 might even be higher but loading rates above 100 mg/L were not tested in accordance with the test guidelines. The 48-hour EC50 and the 48-hour EC100 were clearly higher than the loading rate of 100 mg/L. These values could not be quantified, since the test item had no toxic effects on the daphnids up to the loading rate of 100 mg/L.
In conclusion, the test item FAT 41039/A had no acute toxic effects on Daphnia magna up to the loading rate of 100 mg/L under the present conditions of the test.
Reference
None
Description of key information
The acute toxicity of FAT 41039/A, structural analogue of FAT 41048, to the freshwater invertebrate Daphnia magna was investigated and gave a 48-Hour EC50 value of greater than 100 mg/L. The No Observed Effect Concentration was 100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
No study on toxicity potential of FAT 41048 to aquatic invertebrates is available. However, the acute toxicity of FAT 41039/A, structural analogue of FAT 41048, to Daphnia magna was determined in a 48 hour static test according to the EU Commission Directive 92/69/EEC, Part C.2 (1992) and the OECD Guideline for Testing of Chemcials No. 202 (2004). In order to assess the toxicity of the test item FAT 41039/A containing different components to Daphnia magna, a water accommodated fraction (WAF) was prepared. The method is based on the Guidance Document on Aquatic Toxicity Testing of Difficult Substances and Mixtures (2000).
A limit test was performed in accordance the test guidelines to demonstrate that WAFs of the test item has no toxic effect on the test daphnids up the loading rate of 100 mg/L.
The test item FAT 41039/A had no toxic effect on Daphnia magna up to the loading rate of 100 mg/L. The 48 hour EC50 and NOEC values were determined to be greater than 100 mg/L, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.