Registration Dossier
Registration Dossier
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EC number: 239-198-0 | CAS number: 15137-09-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the physicochemical and toxicological properties suggest no potential for a significant rate of absorption through the skin
- Justification for type of information:
- The EU risk assessment report for edetic acid states:
"No data are available on acute dermal toxicity. Taking into account the poor dermal absorption
(Foremann, 1954), there is reason to assume that the result of an acute dermal toxicity test would
not reveal toxic properties warranting a classification and labelling for acute dermal toxicity."
"Because of the very low activity, the urine from skin absorption studies
required special treatment with the sodium salt of EDTA as carrier. The maximum of activity in
the urine after application over an area of 100 cm² was 0.001%."
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
