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EC number: 480-370-1 | CAS number: 21743-27-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
To assess the acute toxicity of N-(Morpholinomethyl)triethoxysilane to fish a limit test according to OECD 203 (EU Guideline 92/92/EEC C.1) was performed. In the control and the only test concentration (95.7 mg/L mean measured conc.) no mortality and no treatment related toxic effects were observed. Since at a mean concentration of 95.7 mg/L no effect on the test organisms was observed, it can be assumed that the LC50 is also higher than 100 mg/L. Based on this N-(Morpholinomethyl)triethoxysilane is not considered to be toxic to fish.
To assess the acute toxicity of N-(Morpholinomethyl)triethoxysilane to aquatic invertebrates (Daphnia magna) a test according to OECD 202 (EU Guideline 92/92/EEC C.2) was performed. In the control and the concentrations 69, 83, 100 and 120 mg/L (nominal) no immobile daphnids were observed. At the test concentration of 144 mg/L one daphnid was immobile, which was not assessed as significant by statistical evaluation. The measured concentrations were at least 93% of the nominal. Based on this N-(Morpholinomethyl)triethoxysilane is not considered to be toxic to Daphnia magna.
The influence of N-(Morpholinomethyl)triethoxysilane on the growth of the freshwater green algal species Desmodesmus subspicatus was assessed in a static dose-response test (OECD Guideline 201). The 72-hours IC50 value was calculated to be 25.0 mg/L (NOEC: 0.8 mg/L) for the growth rate, and 7.0 mg/L (NOEC: 0.8 mg/L) for the biomass. Thus, it can be concluded that N-(Morpholinomethyl)-triethoxysilane is harmful to the green algal species Desmodesmus subspicatus.
The influence of (N-Morpholinomethyl)triethoxysilane on the activity of activated sludge was evaluated by measuring the respiratory rate under defined conditions (OECD Guideline 209). The respiration rate (oxygen consumption) of an aerobic activated sludge fed with a standard amount of synthetic sewage was measure in the presence of various concentrations of the test item after an incubation period of 3 hours. Based on measured inhibition rates, the 3-hour EC20 and EC50 could not be quantified because up to the highest nominal test concentration of 1000 mg/L less than 20% inhibition was noted after three hours incubation. Nevertheless the 3 -hour EC20 and EC50 are clearly higher than 1000 mg/L under the reported conditions. The positive and the inoculum control worked as expected.
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