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Diss Factsheets
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EC number: 202-908-4 | CAS number: 101-02-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Several guideline studies on aquatic toxicity are available:
- fish (zebra fish): LC50 (96h) > 12 mg/L mean measured (> 100mg/L nominal), NOEC (96h) 2.5 mg/L mean measured (32 mg/L nominal), flow through system
- supporting: fish (golden orfe): LC50 (96h) 22 - 46 mg/L nominal, static system
- Daphnia: EC50 (48h) 0.94 mg/L mean measured, NOEC (48h) < 0.47 mg/L mean measured, static system
- algae: ErC50 (72h) 86 mg/L initial measured test concentration, NOErC (72h) 7.8mg/L initial measured test concentration
- activated sludge: EC50 (3h) > 100mg/L nominal
Toxic effects were observed in the studies with fish, Daphnia and algae. No toxic effects to bacteria were observed.
The tests with fish, algae and Daphnia were performed above the water solubility and the dispersant Tween 80 was used. Furthermore, precipitation was observed. Analytical measurements showed a significant decrease of test substance concentration during the test.
The water solubility of the substance is low (< 0.1mg/L) and the substance is readily biodegradable. Furthermore, the substance contains functional groups subject to hydrolysis. The potential hydrolysis products phenol is according to disseminated data classified as hazardous for the environment (Aquatic Chronic 2, disseminated dossier ECHA, accessed June 25, 2018: self classification). Phenol is readily biodegradable but shows adverse effects to aquatic organisms in acute and chronic studies (di
sseminated dossier ECHA, accessed June 25, 2018). It is unclear if the observed effects were caused by the test substance or its degradation products or if the observed effects were physical effects caused by undissolved particles.
Therefore, the results of the studies with CAS 101 -02 -0 are used as worst case to assess the hazard of the substance.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.