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Diss Factsheets
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EC number: 910-349-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2018-03-22 to 2018-05-02
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187 (2009): Particle Size Analysis by Laser Diffraction
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- Substance H4 HD granules about 0.8 – 4 mm
- Percentile:
- D10
- Mean:
- 476.7 µm
- St. dev.:
- 0
- Remarks on result:
- other:
- Remarks:
- result of one test series
- Key result
- Percentile:
- D50
- Mean:
- 773.9 µm
- St. dev.:
- 0
- Remarks on result:
- other:
- Remarks:
- result of one test series
- Percentile:
- D90
- Mean:
- 1 235.5 µm
- St. dev.:
- 0
- Remarks on result:
- other:
- Remarks:
- result of one test series
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2018-03-22 to 2018-05-02
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 59 (2009): Sieve Analysis
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- sieving
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- Substance H4 HD granules about 0.1 – 2 mm
- Percentile:
- D10
- Mean:
- 379 µm
- St. dev.:
- 0
- Remarks on result:
- other:
- Remarks:
- one measurement performed
- Key result
- Percentile:
- D50
- Mean:
- 1 238 µm
- St. dev.:
- 0
- Remarks on result:
- other:
- Remarks:
- one measurement performed
- Percentile:
- D90
- Mean:
- 1 851 µm
- St. dev.:
- 0
- Remarks on result:
- other:
- Remarks:
- one measurement performed
Referenceopen allclose all
The coarse fraction (>1000 µm) was 93.3 wt.-% and the fine fraction (<1000 µm) 6.7 wt.-%. One test series of 3 measurements was performed with the fine fraction of the test item.
A study was performed in accordance with OECD TG 110, EPA OPPTS 830.7520, CIPAC MT 187 and ISO 13320 in order to determine the particle size distribution of the test item using laser diffraction measurement. One test series of three measurements was performed. The particle size distibution of the test item was determined to be D50= 773.9 µm.
Table 1: Results of sieving analysis
Sieve size in µm |
Weight in g |
Mass % |
Total % |
> 2000 |
0.1 |
0.3 |
100.00 |
< 2000 |
22.5 |
65.2 |
99.7 |
< 1000 |
7.0 |
20.3 |
34.5 |
< 500 |
3.0 |
8.7 |
14.2 |
< 250 |
1.2 |
3.5 |
5.5 |
< 150 |
0.2 |
0.6 |
2.0 |
< 63 |
0.5 |
1.4 |
1.4 |
From these results the particle size distribution for the diameters 10, 50 and 90 Vol.-% were calculated via linear regression.
A study was performed in accordance with OECD TG 110, EPA OPPTS 830.7520 and CIPAC MT 59 in order to determine the particle size distribution of the test item using the sieving analysis. Six sieves with different sizes (2000, 1000, 500, 250, 150 and 63 µm) were used. The whole amount of the test item was filled into the sieve with the largest size and sieved until the amount of the test item in the sieve remained constant. Then the top sieve was removed and the sieving was resumed in the sieve with the next lower size. Each residue in the six single sieves were weighted. From the measured diffraction pattern the particle size distribution for 10, 50 and 90 vol.-% of particles were calculated via linar regression. The median particle size (D50) of the test item was determined to be 1238 µm.
Description of key information
For the test item with granule sizes between 0.8 and 4 mm a median particle size of D50 = 773.9 µm was determined (laser diffraction measurement).
For the test item with granule sizes between 0.1 and 2 mm a median particle size of D50 = 1238 µm was determined (sieving method).
Additional information
As the test item will be produced and marketed with different granule sizes (0.1 to 2 mm and 0.8 to 4 mm) for technical reasons two different studies was performed in order to determine the particle size distribution.
Test item 1 (granule sizes 0.8 to 4 mm) (reference 4.5-1)
A study was performed in accordance with OECD TG 110, EPA OPPTS 830.7520, CIPAC MT 187 and ISO 13320 in order to determine the particle size distribution of the test item using laser diffraction measurement. One test series of three measurements was performed. The particle size distibution of the test item was determined to be D50= 773.9 µm.
Test item 2 (granule sizes 0.1 to 2 mm) (reference 4.5-2)
A study was performed in accordance with OECD TG 110, EPA OPPTS 830.7520 and CIPAC MT 59 in order to determine the particle size distribution of the test item using the sieving analysis.
Six sieves with different sizes (2000, 1000, 500, 250, 150 and 63 µm) were used. The whole amount of the test item was filled into the sieve with the largest size and sieved until the amount of the test item in the sieve remained constant. Then the top sieve was removed and the sieving was resumed in the sieve with the next lower size. Each residue in the six single sieves were weighted. From the measured diffraction pattern the particle size distribution for 10, 50 and 90 vol.-% of particles were calculated via linar regression. The median particle size (D50) of the test item was determined to be 1238 µm.
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