4-pyridylamine

Particle size distribution (Granulometry)

Administrative data

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Deviations:

not specified

GLP compliance:

yes (incl. QA statement)

Type of method:

Laser scattering/diffraction

Type of particle tested:

agglomerate

Type of distribution:

volumetric distribution

Test material

Test material information

Constituent 1

Reference substance name:

4-pyridylamine

EC Number:

207-987-9

EC Name:

4-pyridylamine

Cas Number:

504-24-5

Molecular formula:

C5H6N2

IUPAC Name:

nickel

Test material form:

solid: particulate/powder

Results and discussion

Particle size

Particle size 1

Key result

Percentile:

D50

Mean:

222.9 µm

Remarks on result:

other: st.dev not specified

Particle size 2

Key result

Percentile:

D10

Mean:

28.8 µm

Remarks on result:

other: st.dev not specified

Particle size 3

Key result

Percentile:

D90

Mean:

662.1 µm

Remarks on result:

other: st.dev not specified

Any other information on results incl. tables

Two test series of 3 measurements each were performed with the test item.

Figure 1 and Figure 2 show the results of both test series. On the left y-axis the fraction distribution and on the right y-axis the cumulative distribution is shown.

 

Test series 1 (Figure 1):

D₁₀:       28.5 µm

D₅₀:       221.8 µm       (Median diameter)

D₉₀:       657.7 µm

 

Test series 2 (Figure 2):

D₁₀:       29.1 µm

D₅₀:       223.9 µm       (Median diameter)

D₉₀:       666.4 µm

 

Average

D₁₀:       28.8 µm

D₅₀:       222.9 µm       (Median diameter)

D₉₀:       662.1 µm

Applicant's summary and conclusion

Conclusions:

The test item 4-Aminopyridine has a median particle size D50 = 222.9 µm, which was determined by laser diffraction measurement in accordance to ISO 13320 (2009) and OECD 110 (1981) method.

Executive summary:

The test item 4-Aminopyridine has a median particle size D₅₀ = 222.9 µm, which was determined by laser diffraction measurement in accordance to ISO 13320 (2009) and OECD 110 (1981) method.