Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 219-177-2 | CAS number: 2380-94-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
General information:
If threatening unconsciousness,position and transport in recovery position.
Remove contaminated clothing immediately and dispose it safely.
Adhere to personal protective measures when giving first aid.
In case of breathing difficulties give oxygen.
In case of inhalation:
Seek medical treatment immediately.
In case of respiratory standstill give artifical respiration by respirator and send for a doctor.
In case of skin contact:
If skin irritation or rash occurs: Get medical advice/attention.
In case of contact with skin wash off immediately with soap and water.
Remove contaminated clothing immediately, even underwear and shoes.
In case of eye contact:
In case of contact with eyes rinse thoroughly with plenty of water and seek medical advice.
Remove contact lenses.
In case of ingestion:
Do not induce vomiting.
Call for a doctor immediately.
Provide for plenty of water to be drunken in small gulps (dilution effect). Additionally medical charcoal tablets should be given
Fire-fighting measures
Unsuitable extinguishing media: Full water jet
Accidental release measures
For non-emergency personnel:
Ensure adequate ventilation.
Use personal protective clothing.
Keep away sources of ignition.
Environmental precautions:
Collect contaminated water / firefighting water separately.
Do not discharge into the drains/surface waters/groundwater.
Take up mechanically and send for disposal.
Large spills: contact emergency authorities.
Handling and storage
Advice on safe handling: Transport and store containers always upright.
Advice on storage compatibility:
Do not store with acids.
Do not store with oxidizing agents.
Further information on storage conditions:
Only for expert accessible.
Keep container tightly closed, store at cool and aired place, open and handle carefully.
Protect from light.
Do not store at temperature above 25°C (=77°F).
Protect from heat/overheating.
Keep under dry inert gas.
Protect from exposure to air/oxygen.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3077
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 3077
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Marine transport (UN RTDG/IMDG)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (4-hydroxyindole)
- Chemical name:
- 4-hydroxyindole
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (4-hydroxyindole)
- Chemical name:
- 4-hydroxyindole
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Exposure controls / personal protection
Stability and reactivity
Possibility of hazardous reactions:
Reactions with strong acids and alkalies or strong oxidising agents
Conditions to avoid: Heating (Decomposition!), Exposure to light.
Substances to avoid: Oxidising agents, Acids, Alcalies
Hazardous decomposition products:
Nitrogen oxides (NOx), Carbon monoxide and carbon dioxide, Pyrolysis products, aromatic and aliphatic.
Disposal considerations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.