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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

Description of key information

The substance is not readily biodegradable.

The substance is inherently biodegradable.

Key value for chemical safety assessment

Additional information

As a key study, the non-GLP study was performed according to ISO 7827 part E with an effluent from a domestic STP as inoculum Biodegradation of the test substance (N,N-dibuthylformamide) was followed by DOC measurement. Under the test conditions the test substance was found to be not ready biodegradable over the test period of 29 days. Furthermore, the test substance showed no inhibitory effect on the microorganisms. At the end of the test, the test substance was biodegraded by an average of 11 %. Therefore, the substance is not readily biodegradable under these test conditions.

Results from two non-GLP batch tests (OECD 302B) are available. One study was performed using activated sludge from a domestic sewage treatment plant as inoculum (BASF AG, 1989; report no 84/0764). In the test with industrial activated sludge (BASF AG, 1984), the substance was degraded to 96 % (DOC removal) within 14 days. It can be concluded that the substance is easily eliminated from water. In the other batch test with domestic activated sludge as inoculum, the degradation reached 93% within 22 days based on DOC removal (BASF AG, 1988). It can be concluded hat N,N-dibutylformamide is inherently biodegradable.