Registration Dossier
Registration Dossier
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EC number: 274-152-3 | CAS number: 69847-45-6
Endpoint summary
Administrative data
Description of key information
Acute aquatic toxicity
Algae was the most sensitive species in acute toxicity tests with
the test substance, according to OECD guideline, resulting in a 48-hour
EC50 of 6.83 mg/L (calculated for anhydrous substance). Based on acute
aquatic toxicity results obtained, the substance has not to be
classified according to Regulation (EC) No 1272/2008 (CLP).
Chronic toxicity
The test substance was tested in an aquatic toxicity test with
algae, according to OECD guideline 201. The 72-hour EC50 and EC10 for
growth rate was 6.83 and 1.89 mg/L (calculated for anhydrous substance). Based
on chronic aquatic toxicity results obtained, the substance has not to
be classified according to Regulation (EC) No 1272/2008 (CLP).
Additional information
Short-term toxicity to invertebrates
In the acute immobilisation test (reference 6.1.3-1) with Daphnia magna (STRAUS), the effects of the test item were determined according to OECD Guideline for testing of chemicals, Guideline No. 202, adopted 13th April 2004. The study was conducted in a static system over a period of 48 hours with a nominal concentration of 100 mg/L. The validity criteria of the test guideline were fulfilled. The EC50 value (48 hours) was determined to be > 100 mg/L (hydrated substance) and 85.1 mg/L (calculated for anhydrous substance).
Toxicity to aquatic algae
The effect of the test item on the growth of a unicellular green algal species Raphidocelis subcapitata was determined according to OECD 201, Regulation (EC) No. 226/2016 Method C.3 and EPA OPPTS 850.5400 and under GLP (reference 6.1.5-1). The study was conducted under static conditions with an initial cell density of 1x10^4 cells/mL for a period of 72 hours. Five concentrations were tested in a geometrical series with a dilution factor of 2: 6.25, 12.5, 25, 50 and 100 mg/L ((corresponding to 0.79, 1.11, 1.53, 2.22 and 3.12 mg/L (calculated geometric mean concentrations)). The 72-h EC10, EC20 and EC50 for growth were determined to be 2.22, 3.45 and 8.02 mg/L (hydrated substance), and 1.89, 2.94 and 6.83 mg/L (calculated value for anhydrous substance), respectively. The 72-h EC10, EC20 and EC50 for yield were determined to be 1.08, 1.47 and 2.65 mg/L,(hydrated substance), and 0.92, 1.25 and 2.26 mg/L (calculated value for anhydrous substance), respectively. The results are based on measured geometric mean test item concentrations.
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