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Diss Factsheets
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EC number: 203-626-4 | CAS number: 108-89-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Description of first aid measures
After inhalation:
Remove casualty to fresh air and keep warm and at rest.
In case of irregular breathing or respiratory arrest provide artificial respiration.
Fainting persons should be laid down and carried on their side with sufficient stability.
Seek medical advice.
After skin contact:
Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Following eye contact:
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Continue rinsing for al least 15 min.
After ingestion:
Do NOT induce vomiting.
Rinse mouth immediately and drink large quantities of water.
Seek medical advice.
Never give anything by mouth to an unconscious person or a person with cramps.
Most important syptoms and effects, both acute and delayed
- Acute: Picoline Gamma is corrosive to skin, eyes and mucous membranes. Vapours may irritate the respiratory tract.
Picoline Gamma is readily absorbed through the skin and is considered to be considered orally and dermally toxic.
Prolonged exposure (e.g. from saturated clothing) may cause skin burns and/or systemic intoxication.
Symptoms may include headache, dizziness, nausea, nervousness, weakness, narcosis
include headache, dizziness, nausea, nervousness, weakness, narcosis, insomnia, loss of appetite and possibly loss of consciousness.
Symptoms observed after ingestion or inhalation overexposures are expected to be essentially the same as those observed after ingestion or
ingestion or inhalation overexposures are expected to be essentially the same as those listed above.
Gamma picoline is a corrosive, so damage to the mouth and throat is a possibility if large amounts are ingested.
throat is a possibility if large quantities are ingested.
Ingestion is unlikely to be a primary route of exposure.
- Late Effects: Due to the corrosive nature of this material, burns are likely to occur.
Permanent contact with contaminated clothing may cause burns to appear after a prolonged period of exposure.
Indication of any immediate medical attention and special treatment needed
No data available.
Fire-fighting measures
Extinguishing media
Suitable extinguishing media:
Carbon dioxide (CO2).
Water spray.
Alcohol resistant foam.
Extinguishing powder.
Special hazards arising from the substance or mixture
Fire or excessive heat may produce hazardous decomposition products:
Gas/vapours, toxic.
Cyanide
Azo oxides (NOx)
Carbon monoxide.
Serious risk of explosion in vapour form (within flammability limits) when exposed to heat, flame or static discharge.
Advice for fire-fighters
Wear full chemical protective clothing.
In case of fire: wear self-contained breathing apparatus.
Accidental release measures
Personal precautions, protective equipment and emergency procedures
Keep unprotected people away and stay on the upwind side.
Wear personal protection equipment.
Avoid contact with skin, eyes and clothes
Remove and wash contaminated clothing before reuse.
Leather shoes that have been saturated should be discarded.
Environmental precautions
Do not empty into drains or the aquatic environment.
Methods and material for containment and cleaning up
Provide adequate ventilation
Large spills: dike and pump into appropriate containers for disposal.
Use inert absorbent material (sand, vermiculite, diatomaceous earth, Kieselguhr, etc.) to absorb spilled product.
Treat the assimilated material according to the section on waste disposal.
Use appropriate container to avoid environmental contamination
Reference to other sections
See protective measures under point 7, 8 and 13.
Handling and storage
Precautions for safe handling
Safety measures for handling chemicals must be observed.
Provide adequate ventilation
Evitar la formación de aerosoles.
Avoid contact with skin and eyes.
Wash hands before breaks and immediatley after using the product.
Remove and wash contaminated clothing before reuse.
Protect containers from physical damage.
Use personal protective equipment as required.
Fire and explosion prevention:
Take measures against electrostatic charges.
Keep away from heat/sparks/open flames/hot surfaces.-No smoking
Conditions for safe storage, including any incompatibilities
Requirements with regard to storage and containers:
Keep in cool, well-ventilated place away from:
Strong acid
Oxidising agent
May cause some forms of plastics and rubbers to deteriorate.
Additional information on storage conditions:
Keep container tightly closed
Storage class: Storage of flammable liquids
Specific end use
No data available.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN2313
Shipping information
- Proper shipping name and description:
- PICOLINES
- Chemical name:
- 4-methylpyridine
- Language:
- English
- Class or division:
- Class 3: Flammable liquids
- Subsidiary hazard(s):
- Class 3: Flammable liquids
- Packing group:
- Packing group III: Substances presenting low danger
- Labels:
- 3
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN2313
Shipping information
- Proper shipping name and description:
- PICOLINES
- Chemical name:
- 4-methylpyridine
- Class or division:
- Class 3: Flammable liquids
- Subsidiary hazard(s):
- Class 3: Flammable liquids
- Packing group:
- Packing group III: Substances presenting low danger
- EmS code:
- F-E
- S-D
- Labels:
- 3
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN2313
Shipping information
- Proper shipping name and description:
- PICOLINES
- Chemical name:
- 4-methylpyridine
- Language:
- English
- Class or division:
- Class 3: Flammable liquids
- Subsidiary hazard(s):
- Class 3: Flammable liquids
- Packing group:
- Packing group III: Substances presenting low danger
- Labels:
- 3
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Control parameters
The product does not contain relevant quantities of substances with limit values that require monitoring at the workplace.
Additional information: Use engineering controls to reduce air pollution.
Exposure controls
Individual protections measures, such as personal protective equipment
Respiratory protection:
If ventilation is insufficient, wear respiratory protection:
Chemical respirator with cartridge for organic vapours.
(Filtering Half-face mask DIN EN 149)
Hand protection:
Wear suitable gloves tested to EN374.
The glove material must be impermeable and resistant to the product/substance/preparation.
Gloves material:
Neoprene.
Nitrile.
PVC (Polyvinyl chloride).
Eye protection:
Wear eye glasses with side protection according to EN 166.
Skin protection:
Waterproof protective clothing.
General protection and hygiene measures:
Provide for sufficient ventilation
Avoid contact with skin and eyes.
Avoid ingestion and inhalation.
Wash hands before breaks and immediatley after using the product.
When using do not eat, drink or smoke.
Stability and reactivity
Reactivity
No data available.
Chemical stability
Thermal decomposition / conditions to be avoided:
Stable in recommended storage and handling (see section 7).
Possibility of hazarous reactions
Not known.
Conditions to avoid
Electrostatic charges
Avoid heat, flames and other sources of ignition.
Incompatible materials
Strong acids.
Oxidising agents.
Hazarous decomposition products
Gas/vapours, toxic.
Cyanide
Azo oxides (NOx)
Carbon monoxide.
Disposal considerations
Waste treatment methods
Recommendation: Dispose of in accordance with local authorities.
Uncleaned packaging:
- Recommendation: Dispose of in accordance with official regulations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.