Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-427-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-05-03 to 2017-08-09
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Remarks:
- tox control
- Qualifier:
- according to guideline
- Guideline:
- other: OECD301F
- Version / remarks:
- OECD301F July 1992
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Details on sampling:
- - Concentrations: 128.2 mg/L sodium acetate and 8.3 mg of the test item were added into the toxicity control vessel, corresponding to a concentration of 200.2 mg ThOD/L
- Sampling method: -
- Sample storage conditions before analysis: - - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
128.2 mg/L sodium acetate and 8.3 mg of the test item were added into the toxicity control vessel, corresponding to a concentration of 200.2 mg ThOD/L. The initial pH was 7.6 and was not adjusted. - Test organisms (species):
- activated sludge of a predominantly domestic sewage
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure):
Activated sludge, municipal wastewater treatment plant sludge, municipal wastewater
Breisgauer Bucht, 30 mg dry solids per litre
sampling 2017-05-03
- Laboratory culture: no
- Method of cultivation: no
- Storage conditions: not mentioned
- Storage length: 1d
- Preparation of inoculum for exposure:
The activated sludge was washed twicece with tap
water by settling the sludge, decanting the supernatant and re-suspending the sludge
- Pretreatment:
- Concentration of sludge: 30 mg dry solids per litre
- Initial cell/biomass concentration:
- Water filtered: yes/no
- Type and size of filter used, if any: - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 28 d
- Key result
- Duration:
- 28 d
- Dose descriptor:
- IC0
- Effect conc.:
- 50 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: inhibition of respiration of reference substance sodium acetate according to the criteria of OECD301F
- Details on results:
- The degradatiion in the toxiicity control reached a value higher than 25% within 4 days. According to the validity criterion of the guideline OECD 301 the test item had no toxic effect to the inoculum.
The pH in the toxicity control vessel at the end of the test was 8.6. - Results with reference substance (positive control):
- The reference compound sodium acetate reached the pass level for ready biodegradability (60% ThOD within a 10-day window) within 8 days.
- Validity criteria fulfilled:
- yes
- Conclusions:
- In a test on readily biodegradablility according to OECD301F, the test substance has no inhibitory effect on the degradation of sodium acetate at a concentration of 50mg/l.
Reference
Degradation table
|
|
Test item |
|
Toxicity control |
Reference item |
||
Test item |
8.3 |
8.4 |
8.4 |
8.3 |
|
|
|
[mg /164 ml] |
|
|
|
|
|
|
|
Reference item |
|
|
|
164 |
164 |
164 |
164 |
ThOD [mg/1] |
100.2 |
101.4 |
101.4 |
200.2 |
100.0 |
100.0 |
100.0 |
Day |
|
|
Degradation {%] |
|
|
||
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
4 |
13.0 |
15.6 |
21.3 |
27.6 |
55.3 |
55.3 |
55.3 |
8 |
35.6 |
35.2 |
46.2 |
37.5 |
66.6 |
69.4 |
66.6 |
12 |
51.5 |
53.7 |
62.0 |
46.7 |
74.1 |
76.9 |
74.1 |
16 |
60.8 |
65.6 |
68.4 |
55.7 |
75.1 |
77.6 |
77.6 |
20 |
65.5 |
70.3 |
70.3 |
62.4 |
73.8 |
79.8 |
71.3 |
24 |
72.1 |
73.7 |
73.7 |
72.8 |
74.8 |
83.8 |
74.8 |
28 |
71.2 |
75.8 |
75.8 |
77.8 |
76.8 |
82.8 |
73.8 |
Description of key information
In a test on readily biodegradablility according to OECD301F, the test substance has no inhibitory effect on the degradation of sodium acetate at a concentration of 50mg/l.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 50 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.