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EC number: 203-293-5 | CAS number: 105-38-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 8 - 18 May 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- yes
- Remarks:
- see principles of method if other than guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Regulation (EC) No 440/2008
- Deviations:
- yes
- Remarks:
- see principles of method if other than guideline
- Principles of method if other than guideline:
- The temperature in the equilibration phase ranged from 19.2 to 19.8 °C, with a mean of 19.5 °C and was thus out of the range of 20 ± 0.5 °C. This should have had no influence on the study, as the deviation was minor and the overall mean was in the range given by the guideline.
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- chemical analyses were performed non-GLP
- Type of method:
- flask method
Test material
- Reference substance name:
- Vinyl propionate
- EC Number:
- 203-293-5
- EC Name:
- Vinyl propionate
- Cas Number:
- 105-38-4
- Molecular formula:
- C5H8O2
- IUPAC Name:
- ethenyl propanoate
- Reference substance name:
- Unknown impurities.
- Molecular formula:
- Not available as unknown impurities.
- IUPAC Name:
- Unknown impurities.
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Oxidane
- Test material form:
- liquid: volatile
- Details on test material:
- Batch No: 57161235
Storage: Room temperature (approx. 20°C)
Constituent 1
impurity 1
impurity 2
Results and discussion
Water solubility
- Key result
- Water solubility:
- 7.52 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Temp.:
- 20 °C
- pH:
- >= 3.5 - <= 3.9
- Details on results:
- Preliminary test
This preliminary test indicated a water solubility of 1 to 10 g/L.
Main test
Since the results after one, two and three days showed increasing concentrations, the test was prolonged by using longer equilibration times, and the concentration was also determined after eight days.
The test vessels from all samplings were considered to obtain the final result, because no significant variation of the test item concentration was observed over the whole test duration.
The results are given in the table in the next section.
The individual results of the test vessels, which were deemed constant, were averaged and are given in mass per volume of solution. The test is satisfactory if the concentrations of at least the last 2 vessels do not differ by more than 15%.
Any other information on results incl. tables
GC-MS determinations:
Test vessel | pH | Analysed concentration A (g/L) | Analysed concentration B (g/L) | Analysed concentration C (g/L) | Mean (g/L) |
No. 1 | 3.9 | 6.99 | 7.41 | 7.24 | 7.22 |
No. 2 | 3.8 | 7.27 | 7.46 | 8.16 | 7.63 |
No. 3 | 3.7 | 7.88 | 8.38 | 7.83 | 8.03 |
No. 4 | 3.5 | 7.15 | 7.02 | 7.44 | 7.20 |
Overall Mean | 7.52 |
The concentrations of the three vessels differed by 11% (validity criterion given by OECD is met).
Applicant's summary and conclusion
- Conclusions:
- The water solubility of Vinyl propionate (CAS 105-38-4) was determined according to TG OECD 105.
The water solubility of the test item at 20 °C was 7.52 g/L. The pH of the aqueous samples was 3.5 to 3.9. - Executive summary:
The water solubility of Vinyl propionate (CAS no. 105-38-4) was determined according to TG OECD 105.
Several test vessels containing ultra-pure water mixed with test item in great excess (initial amount of test item about 50 g per liter water), were incubated and stirred for different periods of time at about 30 °C (saturation phase), and then transferred to about 20 °C for 24 h (equilibration phase). Samples were taken from the middle of the solution by syringe, as undissolved test item swam on the surface of the test solution. The concentration of test item in the clear aqueous phase was determined with purge and trap GC-MS.
The measured concentrations were as follows:
7.22 g/L after one day at 30 °C, followed by 24 h at 20 °C, pH 3.9
7.63 g/L after two days at 30 °C, followed by 24 h at 20 °C, pH 3.8
8.03 g/L after three days at 30 °C, followed by 24 h at 20 °C, pH 3.7
7.20 g/L after eight days at 30 °C, followed by 24 h at 20 °C, pH 3.5
Since the results after one, two and three days showed increasing concentrations, the test was prolonged by using longer equilibration times, and the concentration was also determined after eight days.
The test vessels from all samplings were considered to obtain the final result, because no significant variation of the test item concentration was observed over the whole test duration.
The water solubility of Vinyl propionate, calculated as the mean of all four test vessels, is 7.52 g/L at a pH of 3.5 to 3.9 and ca. 20 °C.
The validity criterion was fulfilled.
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