Registration Dossier
Registration Dossier
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EC number: 210-043-9 | CAS number: 603-48-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- OASIS Catalogic v5.12.1
QPRF and QMRF are attached in IUCLID - GLP compliance:
- no
Test material
- Reference substance name:
- N,N,N',N',N'',N''-hexamethyl-4,4',4''-methylidynetrianiline
- EC Number:
- 210-043-9
- EC Name:
- N,N,N',N',N'',N''-hexamethyl-4,4',4''-methylidynetrianiline
- Cas Number:
- 603-48-5
- Molecular formula:
- C25H31N3
- IUPAC Name:
- 4-{bis[4-(dimethylamino)phenyl]methyl}-N,N-dimethylaniline
- Details on test material:
- - Purity: Not applicable
Smiles: CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1
Constituent 1
- Specific details on test material used for the study:
- Smiles: CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.11 mg/L
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- 72-hour EC50 (algae): 0.11 mg/L
- Executive summary:
OASIS Catalogic v5.12.1 was used. The model predicts a 72-hour EC50 value of 0.11 mg/L in green algae. Additional supporting documentation is provided in the prediction report attached in IUCLID.
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