Registration Dossier
Registration Dossier
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EC number: 240-387-5 | CAS number: 16298-03-6
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 February 2013 - 26 April 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Version / remarks:
- (2008)
- Deviations:
- yes
- Remarks:
- The temperature of the oven was increased to 400°C although the melting temperature of the substance is lower.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Methyl 3-aminopyrazinecarboxylate
- EC Number:
- 240-387-5
- EC Name:
- Methyl 3-aminopyrazinecarboxylate
- Cas Number:
- 16298-03-6
- Molecular formula:
- C6H7N3O2
- IUPAC Name:
- methyl 3-aminopyrazine-2-carboxylate
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study report): Amiloride Compound 6
- Description: Tan powder
- Storage condition of test material: In refrigerator (2-8°C) protected from light, desiccated
- Other: Reactive to light, moisture and oxygen
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Remarks on result:
- no self-ignition observed up to the melting point
Any other information on results incl. tables
No endothermic or exothermic reaction between 20°C and 400°C. After the experiment, the test substance had turned into a charred residue and was collected in a container that was placed below the cube. It indicated that the test substance had been molten, decomposed and/or reacted during the experiment. This is in line with the melting temperature of the substance (170°C:see endpoint 4.2).
Applicant's summary and conclusion
- Conclusions:
- The relative self-ignition test was performed (in accordance with EC A.16 and in compliance with GLP), not resulting in a temperature at which self-ignition took place.
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