Registration Dossier
Registration Dossier
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EC number: 231-954-8 | CAS number: 7782-41-4
Endpoint summary
Administrative data
Description of key information
Additional information
No aquatic toxicity studies with fluorine are available or can be performed as in contact with water fluorine reacts instantly and violently under formation of hydrogen fluoride. Hydrogen fluoride will further react to fluoride. Therefore available data from studies with fluoride, are given as indication of the aquatic toxicity of fluorine.
Short-term toxicity to fish
For fluoride several studies performed with sodium fluoride in different fish species are available. From these studies, the lowest effect value is a 96-h LC50 of 51 mg fluoride/L in rainbow trout.
Long-term toxicity to fish
In a 21 day test withOncorhynchus mykiss, reviewed in the ICD and EU RAR, an LC5 value of 4 mg/L is reported (actual concentration). This value is considered to be equivalent to the NOEC for mortality. The test was conducted in very soft (12 mg CaCO3/L) natural water with daily renewal of the test water.
Short-term toxicity to aquatic invertebrates
For fluoride several studies performed with sodium fluoride in different aquatic invertebrates are available. From these studies, the lowest effect value is a 96-h EC50 of 26 mg fluoride/L in benthic macroinvertebrates.
Long-term toxicity to aquatic invertebrates
The EU RAR summarises the effects of two reproductive studies of sodium fluoride on Daphnia magna. The two studies report NOEC values of 3.7 and 14.1 mg/L, with an arithmetic mean of 8.9 mg fluoride/L.
Toxicity to algae
The EU RAR reviews and summarises the available data on the toxicity of sodium fluoride to freshwater and marine algae species. The EC50 values for freshwater algae are reported to range from 43 to 122 mg/L. For marine algae the EC50 was 81 mg/L in a single study with Skeletonema costatum. NOEC values of 50-249 mg/L and 50-200 mg/L are reported for freshwater and marine algae, respectively.
Toxicity to microorganisms
For fluoride several studies performed with sodium fluoride in different microorganisms are available. From these studies, only two can theoretically be used for deriving a PNEC for fluoride. The critical effect value is a 3-h EC10 value of 510 mg fluoride/L in activated sludge.
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