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Diss Factsheets
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EC number: 308-067-0 | CAS number: 97862-23-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short term toxicity to fish:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Long term toxicity to fish:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Short term toxicity to aquatic invertebrates:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Long term toxicity to aquatic invertebrates:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Toxicity to aquatic algae and cyanobacteria:
Freshwater algal growth inhibition test was carried out on Desmodesmus subspicatus with the substance according to OECD Guideline 201. The stock solution 10 mg/l was prepared by dissolving dark liquid in acetone. Test solutions of required concentration were prepared by mixing the stock solution of the test sample with OECD growth medium and inoculum culture. It was not possibile to test higher concentrations of sample because of low solubilities thus chemical dissolved in the acetone. Test conducted on 0, 0, 2.3, 3.4, 5, 7.4, 10.8 mg/l nominal concentration in static system. Potassium dichromate used as a positive control. ErC50 is calculated from the inhibition of growth rate by non-linear regression using software Prism 4.0, GraphPad. Effects on the growth rate of the organism were studied after the exposure period of 72 hrs. The median effective concentration (ErC50) for the test substance, in Desmodesmus subspicatus was determined to be 15.7 mg/L on the basis of effects on growth rate in a 72 hour study. This value indicates that the substance is likely to be hazardous to aquatic algae and can be classified as aquatic chronic 3 category as per the CLP criteria. The test chemical is as such insoluble in water and hence for the experiment performed the test chemical was dissolved in acetone as the solvent. It is likely that acetone can interfere with the toxicity observed. In natural conditions, the test chemical will be exposed to the test organism in water and as it is insoluble in water, it is less likely to affect the growth of algae and cyanobacteria. Based on the above criteria it can be concluded that the chemical was not toxic and cannot be classified as per the CLP classification criteria.
The test chemical is as such insoluble in water and hence for the experiment performed the test chemical was dissolved in acetone as the solvent. It is likely that acetone can interfere with the toxicity observed. In natural conditions, the test chemical will be exposed to the test organism in water and as it is insoluble in water, it is less likely to affect the growth of algae and cyanobacteria. Based on the above criteria it can be concluded that the chemical was not toxic and cannot be classified as per the CLP classification criteria.
Toxicity to microorganisms:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
The test chemical is as such insoluble in water and hence for the experiment performed the test chemical was dissolved in acetone as the solvent. It is likely that acetone can interfere with the toxicity observed. In natural conditions, the test chemical will be exposed to the test organism in water and as it is insoluble in water, it is less likely to affect the growth of algae and cyanobacteria. Based on the above criteria it can be concluded that the chemical was not toxic and cannot be classified as per the CLP classification criteria.
Additional information
Short term toxicity to fish:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Long term toxicity to fish:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Short term toxicity to aquatic invertebrates:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Long term toxicity to aquatic invertebrates:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
Toxicity to aquatic algae and cyanobacteria:
Freshwater algal growth inhibition test was carried out on Desmodesmus subspicatus with the substance according to OECD Guideline 201. The stock solution 10 mg/l was prepared by dissolving dark liquid in acetone. Test solutions of required concentration were prepared by mixing the stock solution of the test sample with OECD growth medium and inoculum culture. It was not possibile to test higher concentrations of sample because of low solubilities thus chemical dissolved in the acetone. Test conducted on 0, 0, 2.3, 3.4, 5, 7.4, 10.8 mg/l nominal concentration in static system. Potassium dichromate used as a positive control. ErC50 is calculated from the inhibition of growth rate by non-linear regression using software Prism 4.0, GraphPad. Effects on the growth rate of the organism were studied after the exposure period of 72 hrs. The median effective concentration (ErC50) for the test substance, in Desmodesmus subspicatus was determined to be 15.7 mg/L on the basis of effects on growth rate in a 72 hour study. This value indicates that the substance is likely to be hazardous to aquatic algae and can be classified as aquatic chronic 3 category as per the CLP criteria. The test chemical is as such insoluble in water and hence for the experiment performed the test chemical was dissolved in acetone as the solvent. It is likely that acetone can interfere with the toxicity observed. In natural conditions, the test chemical will be exposed to the test organism in water and as it is insoluble in water, it is less likely to affect the growth of algae and cyanobacteria. Based on the above criteria it can be concluded that the chemical was not toxic and cannot be classified as per the CLP classification criteria.
The test chemical is as such insoluble in water and hence for the experiment performed the test chemical was dissolved in acetone as the solvent. It is likely that acetone can interfere with the toxicity observed. In natural conditions, the test chemical will be exposed to the test organism in water and as it is insoluble in water, it is less likely to affect the growth of algae and cyanobacteria. Based on the above criteria it can be concluded that the chemical was not toxic and cannot be classified as per the CLP classification criteria.
Toxicity to microorganisms:
In accordance with column 2 of Annex VIII of the REACH regulation, testing for this end point is considered scientifically unjustified since there are mitigating factors indicating that aquatic toxicity is unlikely to occur as the substance is highly insoluble (solubility: < 0.01 mg/L at 25° C) in water. Thus chemical can be considered to be hydrophobic in nature.
The test chemical is as such insoluble in water and hence for the experiment performed the test chemical was dissolved in acetone as the solvent. It is likely that acetone can interfere with the toxicity observed. In natural conditions, the test chemical will be exposed to the test organism in water and as it is insoluble in water, it is less likely to affect the growth of algae and cyanobacteria. Based on the above criteria it can be concluded that the chemical was not toxic and cannot be classified as per the CLP classification criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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