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EC number: 500-740-9 | CAS number: 162492-07-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From November 7, 2002 to November 15, 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: screening test
- Media:
- soil
- Specific details on test material used for the study:
- CAS No.: 162492-07-1; Purity: treated as 100% pure; Appearance: white to off-white solid
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Details on sampling:
- Soil preparation:
Representative samples of Soils I (Cranfield 115 clay loam), 11 (Cranfield 164 silt loam) and 111 (Cranfield 243 sandy loam) were taken from storage and their soil moisture content was determined after oven drying of a 50 g sample at 105 °C until constant weight. - Matrix no.:
- #1
- Matrix type:
- clay loam
- % Clay:
- 32.76
- % Silt:
- 23.5
- % Sand:
- 43.74
- % Org. carbon:
- 1.7
- pH:
- > 7.4 - < 7.9
- CEC:
- 19.6 meq/100 g soil d.w.
- Matrix no.:
- #2
- Matrix type:
- silt loam
- % Clay:
- 11.14
- % Silt:
- 72.91
- % Sand:
- 15.95
- % Org. carbon:
- 3
- pH:
- > 6.5 - < 7.1
- CEC:
- 18.1 meq/100 g soil d.w.
- Matrix no.:
- #3
- Matrix type:
- sandy loam
- % Clay:
- 13.55
- % Silt:
- 13.12
- % Sand:
- 73.33
- % Org. carbon:
- 1.1
- pH:
- > 4.5 - < 5.6
- CEC:
- 12.7 meq/100 g soil d.w.
- Details on matrix:
- Clay loam:
Water holding capacity (%): 55.3
% moisture at 1/3 bar: 30.4
Silt loam:
Water holding capacity (%): 72.8
% moisture at 1/3 bar: 41.2
Sandy loam:
Water holding capacity (%): 49.4
% moisture at 1/3 bar: 16.9 - Details on test conditions:
- Treatment solution:
On the day of spiking a stock solution (StA) containing 3.596 g test substance/L in methanol was prepared. The treatment solution (Spike 1) was prepared by diluting 556 uL of the stock solution to 1 L with 0.01 M aqueous CaCI2 solution. This is equivalent to 2.00 mg test substance/L. The amount of organic co-solvent (methanol) in the treatment solution was 0.06 %. The treatment solution was analysed using LC-MSMS) on the day of spiking (intermediate storage in the refrigerator at 5-10 °C) The water solubility of the test substance is 12 mg/L. The test substance concentration in the treatment solution was therefore equivalent to 17 % of the water solubility. - Key result
- Sample No.:
- #1
- Type:
- other: Kom
- Value:
- 6 400 other: cm3/g
- pH:
- 7.9
- Matrix:
- (Cranfield 115 day loam)
- % Org. carbon:
- 2.9
- Remarks on result:
- other: Corresponding Koc: 110000 cm3/g
- Key result
- Sample No.:
- #2
- Type:
- other: Kom
- Value:
- 3 700 other: cm3/g
- pH:
- 7.1
- Matrix:
- (Cranfield 164 silt loam)
- % Org. carbon:
- 5.2
- Remarks on result:
- other: Corresponding Koc: 6330 cm3/g
- Key result
- Sample No.:
- #3
- Type:
- other: Kom
- Value:
- 730 other: cm3/g
- pH:
- 5.6
- Matrix:
- (Cranfield 243 sandy loam)
- % Org. carbon:
- 1.9
- Remarks on result:
- other: Corresponding Koc: 1260 cm3/g
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the study conditions, the test substance can be considered immobile in Cranfield 115 day loam, Cranfield 164 silt loam and Cranfield 243 sandy loam. Mean Kom values were 6400, 3700 and 730 cm3/g for the three soils, respectively. The corresponding Koc values were 110000, 6330 and 1260 cm3/g. The average Koc over the three soils was 39197 cm3/g.
- Executive summary:
A study was conducted to determine the adsorption/desorption coefficient of the test substance according to OECD Guideline 106, in compliance with GLP. The adsorption behaviour was studied in three soils: Cranfield 115 (2.9% organic matter (OM), day loam), Cranfield 164 (5.2% OM, silt loam) and Cranfield 243 (1.9% OM, sandy loam). Adsorption coefficients were determined at an initial test substance concentration of 1.71 mg/L. Desorption was evaluated using two consecutive desorption steps with fresh 0.01 M aqueous CaCl2 solutions. The experiments were carried out at 20 ± 1°C in the dark. The soil supernatants were analysed using LC-MSMS. Under the study conditions, the test substance can be considered immobile in Cranfield 115 day loam, Cranfield 164 silt loam and Cranfield 243 sandy loam. Mean Kom values were 6400, 3700 and 730 cm3/g for the three soils, respectively. The corresponding Koc values were 110000, 6330 and 1260 cm3/g. The average Koc over the three soils was 39197 cm3/g (van Noorloos, 2003).
Reference
Description of key information
Key value for chemical safety assessment
- Koc at 20 °C:
- 39 197
Additional information
A study was conducted to determine the adsorption/desorption coefficient of the test substance according to OECD Guideline 106, in compliance with GLP. The adsorption behaviour was studied in three soils: Cranfield 115 (2.9% organic matter (OM), day loam), Cranfield 164 (5.2% OM, silt loam) and Cranfield 243 (1.9% OM, sandy loam). Adsorption coefficients were determined at an initial test substance concentration of 1.71 mg/L. Desorption was evaluated using two consecutive desorption steps with fresh 0.01 M aqueous CaCl2 solutions. The experiments were carried out at 20 ± 1°C in the dark. The soil supernatants were analysed using LC-MSMS. Under the study conditions, the test substance can be considered immobile in Cranfield 115 day loam, Cranfield 164 silt loam and Cranfield 243 sandy loam. Mean Kom values were 6400, 3700 and 730 cm3/g for the three soils, respectively. The corresponding Koc values were 110000, 6330 and 1260 cm3/g. The average Koc over the three soils was 39197 cm3/g (van Noorloos, 2003).
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