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Diss Factsheets
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EC number: 214-492-1 | CAS number: 1135-40-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to microorganisms: EC0 ≥ 92 mg/L, NOEC ≥ 92 mg/L over 28 days for activated sludge of a predominantly domestic sewage (OECD 301F)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 92 mg/L
Additional information
To cover this endpoint the toxicity control data from the (for this endpoint) Klimisch 2 OECD 301F study has been used, revealing EC0, NOEC ≥ 92 mg/L (28d) - which is the only dose tested in the OECD 301F - and sufficiently reliable to assess the toxicity of CAPS to microorganisms. This is in line with the endpoint specific guidance R7b (v 3.0, Febr. 2016), where the following is stated regarding toxicity on STP microorganisms and the use of data from biodegradation tests (second criteria applicable for CAPS):
"The information content of ready or inherent biodegradability tests can also be used to derive a NOEC under the following conditions:
• when in a ready or inherent biodegradability test the compound is found to be respectively readily or inherently biodegradable,
• when in a ready or inherent biodegradability test a toxicity control has been included that shows good degradation of a positive control substance (e.g. glucose, sodium acetate) in the presence of the test substance."
The toxicity control attained 43 % after 14 days and 53.8 % degradation at the end of the test. If degradation in the toxicity flask is below 25% after 14 days, the test item can be considered as toxic towards the inoculum. This is not the case here. With regard to the CLP Regulation 1272/2008, the results do not trigger classification of CAPS as hazardous to the environment, as it isn't part of the classification criteria. Accordingly, it can be considered as harmless to the aquatic environment. There is no indication given that the results from this study are not reliable, the data requirements according to REACH Annex VIII are met and no need for further testing was identified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.