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EC number: 205-447-7 | CAS number: 141-01-5
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Experimental data of read across chemicals
- Justification for type of information:
- Data is from collection of data
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- WoE was prepared for the determination of biodegradation rate of test chemical in water.
- GLP compliance:
- not specified
- Oxygen conditions:
- not specified
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- WoE 2 and 3
- Concentration of sludge: 30 mg/l - Duration of test (contact time):
- 14 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- WoE 2 and 3
- Parameter followed for biodegradation estimation:
- TOC removal
- Remarks:
- WoE 2 and 3
- Parameter followed for biodegradation estimation:
- other: HPLC
- Remarks:
- WoE 2 and 3
- Details on study design:
- WoE 2 and 3:
Standard type - Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 70
- Sampling time:
- 14 d
- Remarks on result:
- other: Other detaills not known
- Remarks:
- WoE 2
- Parameter:
- % degradation (O2 consumption)
- Value:
- 87
- Sampling time:
- 14 d
- Remarks on result:
- other: WoE 3
- Parameter:
- % degradation (TOC removal)
- Remarks:
- and HPLC
- Value:
- 100
- Sampling time:
- 14 d
- Remarks on result:
- other: Other detaills not known
- Remarks:
- WoE 2 and 3
- Details on results:
- WoE 2: Test substance undergoes 70 and 100% degradation by BOD, TOC removal and HPLC parameter in 14 days.
WoE 3: Test substance undergoes 87 and 100% degradation by BOD, TOC removal and HPLC parameter in 14 days. - Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The percentage degradation of test substance was determined to be 70 and 87 % by BOD and 100 % by TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
- Executive summary:
Summarized result for the determination of biodegradation of test chemical in water are as mentioned below:
In the first key study from authoritative database, biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of test substance. Activated sludge was used for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance concentration used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 70 and 100 % by BOD, TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
Above study further supported by the second study from authoritative database. Biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of test substance. Activated sludge was used for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance concentration used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 87 % by BOD and 100% by TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
Thus, on the basis of above all studies, the percentage degradation of test substance was determined to be 70 and 87 % by BOD and 100 % by TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
Reference
Description of key information
The percentage degradation of test substance was determined to be 70 and 87 % by BOD and 100 % by TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Summarized result for the determination of biodegradation of test chemical and structurally and functionally similar read across chemicals in water are as mentioned below:
In the first key study from authoritative database, biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of test substance. Activated sludge was used for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance concentration used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 70 and 100 % by BOD, TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
Above study further supported by the second study from authoritative database. Biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of test substance. Activated sludge was used for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance concentration used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 87 % by BOD and 100% by TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
Thus, on the basis of above all studies, the percentage degradation of test substance was determined to be 70 and 87 % by BOD and 100 % by TOC removal and HPLC parameter in 14 days. Thus, based on percentage degradation, test chemical was considered to be readily biodegradable in water.
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