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EC number: 412-540-8 | CAS number: 22471-55-2 ET 344 SP
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Details on sampling:
- Solutions of the test material were prepared at approximately 10 mg/l in the buffer solutions and maintained at 50°C for 5 days.The concentration of test material was monitored by gas chromatography as follows:
Samples
50 ml of each sample was extracted with three 15 ml portions of dichloromethane, each extract being filtered through anhydrous sodium sulphate. The combined extracts were then diluted to 50 ml using dichloromethane. This was performed in duplicate, (A and B), for the Initial, 2.4 hour, 24 hour and 120 hour samples
Standards
Standard solutions were prepared in dichloromethane at a nominal concentration of 10 mg/l. - Buffers:
- SPECIFICATION OF BUFFER SOLUTIONS:
pH4
Citric acid 0.05 mol . dm-3
Sodium hydroxide 0.10 mol .dm-3
Hydrochloric acid 0.05 mol . dm-3pH7
Disodium hydrogen orthophosphate 0.04127 mol .dm-3
Potassium dihydrogen orthophosphate 0.0282 mol . dm-3
pH9
Disodium tetraborate 0.05 mol .dm-3
Hydrochloric acid 0.0192 mol .dm-3 - Duration:
- 2.4 h
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 24 h
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 120 h
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 2.4 h
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 24 h
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 120 h
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 2.4 h
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 24 h
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 120 h
- pH:
- 9
- Temp.:
- 50 °C
- Number of replicates:
- Duplicates (A and B)
- Positive controls:
- no
- Negative controls:
- no
- Statistical methods:
- none
- Preliminary study:
- none
- Transformation products:
- not specified
- % Recovery:
- > 90
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 5 d
- Remarks on result:
- not determinable
- % Recovery:
- > 90
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 5 d
- Remarks on result:
- not determinable
- % Recovery:
- > 90
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 5 d
- Remarks on result:
- not determinable
- Key result
- Remarks on result:
- not measured/tested
- Details on results:
- See enclosed pdf document
- Validity criteria fulfilled:
- yes
- Conclusions:
- ET-344 SP was found to undergo less than 10% hydrolysis after 5 days at 50°C in pH 4, 7 and 9 buffer solutions.
- Executive summary:
EU method C.7 was followed
Solutions of the test material were prepared at approximately 10 mg/l in the buffer solutions and maintained at 50°C for 5 days
The concentration of test material was monitored by gas chromatography
ET-344 SP was found to undergo less than 10% hydrolysis after 5 days at 50°C in pH 4, 7 and 9 buffer solutions.
Reference
Description of key information
EU method C.7 was followed
Solutions of the test material were prepared at approximately 10 mg/l in the buffer solutions and maintained at 50°C for 5 days
The concentration of test material was monitored by gas chromatography
ET-344 SP was found to undergo less than 10% hydrolysis after 5 days at 50°C in pH 4, 7 and 9 buffer solutions.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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