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Diss Factsheets
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EC number: 406-690-3 | CAS number: 43136-14-7 MDI/ODA
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
A ready biodegradation study demonstrated 7.8 % degradation after 28 days in a study performed according to the European Union method C.5 (Degradation: Biochemical Oxygen Demand) (1991). The substance is therefore considered to not be readily biodegradable and is potentially persistent or very persistent based on the screening criteria.
Two calculated partition coefficient values ranged from 19.07 to 21. Log Kow values above 10 show that the uptake of the substance may be hindered in organisms. Both predicted log Kow values are greater than 10, indicating that the uptake and therefore bioaccumulation of the substance may be limited. The substance has a low water solubility of <0.9 mg/L at 20⁰C. Based on the very low solubility and very high partition coefficient of the isolated substance, limited uptake in the aquatic environment is expected. Additionally, the substance is manufactured and used in base oil which will further reduce the bioavailability of the substance and its bioaccumulation potential. It can therefore be concluded that the substance is not bioaccumulative based on a Weight-of-Evidence approach using expert judgement.
Three acute toxicity studies were performed (Daphnia sp. Acute immobilisation test; acute toxicity to fish test andFreshwater Alga and Cyanobacteria, Growth Inhibition Test). The results from all the studies showed that no acute toxicity occurred at the maximum solubility limit or at the highest tested concentration of the test item. Therefore, no evidence of toxicity was observed in the available studies and the substance is considered to be unlikely to be toxic, but chronic ecotoxicity data are not available to compare against the definitive toxicity criteria.
Overall, as the substance is not bioaccumulative and unlikely to be toxic, the substance is not considered to be PBT or vP/vB.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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